Multi-targeted therapeutics to treat complex diseases
Harmonic Discovery is a venture-backed biotechnology company leveraging biology, medicinal chemistry, and machine learning to create a new generation of multi-targeted therapeutics for oncology and autoimmune disorders.
Harmonic Discovery is committed to a multicultural work environment. We strongly encourage applications from women and underrepresented minorities.
The company is seeking a Vice President of Drug Discovery and Development to lead the development of preclinical drug development programs from concept through IND submission and beyond. This candidate will interact with scientists in the design and completion of studies to determine the function of prioritized targets as well as the execution of in vitro and in vivo assays to support the progression of drug discovery programs.
This candidate will be a part of a multidisciplinary team, interacting with the machine learning, bioinformatics, and medicinal chemistry teams to guide the design of multi-specific therapeutics that bind to several targets implicated in disease. The candidate will also work with collaborating academic laboratories and contract research organizations to support and manage internal research efforts.
• MD/Ph.D/PharmD. with a strong background in Cell Biology, Molecular Biology, Chemistry, Oncology, Immunology, Pharmacology or related fields.
• 10+ years of drug discovery experience in biotech and/or pharmaceutical companies with demonstrated success in small molecule drug discovery.
• Proven track record leading teams in drug development from concept to clinical trials.
• Experience with kinase assays and phenotypic responses of cancer cell lines.
• Experience working with external CROs to optimize internal/external resources.
• Strong strategic, scientific, and technical leadership.
• Ability to critically analyze and interpret data, and effective communication skills.
• Collaborative, team-oriented mindset.
• Competitive salary, equity and benefits package including medical, dental and vision insurance, significant paid vacation, and personal leave and 401(k) matching.
• High degree of flexibility. Candidates may work from anywhere in the US if they have a stable internet connection.
Harmonic Discovery is an equal opportunity employer. Harmonic Discovery recruits and employs regardless of race, religion, color, national origin, sex, disability, age, veteran status, and other protected status as required by applicable law.
We are a drug discovery company developing a new generation of therapeutics that embrace the complexity of disease. Currently available approaches for creating drugs work on the principal of finding one drug-one protein 'magic bullets'. However, diseases such as cancer and autoimmunity are often the result of several dysregulated proteins across many distinct biological pathways.
We are building a computational-experimental platform to design therapeutics that can target several disease-causing proteins at once. By designing multi-specific drugs, we are able to create therapeutics that are more efficacious and safer than existing medicines.