Health Tech Startups funded by Y Combinator (YC) 2026

Our Why At Clipboard, our mission is to uplift as many communities as possible. We do this by connecting professionals with the workplaces that need amazing workers, helping people achieve financial stability for themselves and their families all across the U.S. Our How Clipboard is an app-based marketplace where workplaces post calls for help and workers answer. Every year, we help hundreds of thousands of workers fill millions of shifts across the U.S. We’re the leader in Long-Term Care staffing and are rapidly expanding into Home Health, Hospitals, and more. Our Team Founded in 2016, we are a remote-first team of over 1,000 people working to uplift communities across the country.

Astraea is an AI-native biometrics platform for clinical trials. We automate the data management, statistical programming, and clinical data analysis workflows that take Phase II and III studies from raw study inputs to auditable, FDA-ready outputs. Instead of relying on fragmented legacy systems, manual handoffs, and large programming teams, Astraea gives sponsors a single platform to move from source data through standards generation, analysis datasets, tables/listings/figures, and final reporting with human oversight built in. Our platform is designed for the parts of clinical development that are still painfully manual today: raw data ingestion, data normalization, CDISC mapping, SDTM generation, ADaM transformation, TFL production, QC cycles, and revision workflows. We unify these steps in one system so teams can track the entire data analysis pipeline from a single interface, with full visibility, version control, auditability, and traceability at every stage. In practice, Astraea helps sponsors and biometrics teams replace months of repetitive expert work with automated, reviewable execution. Highly trained statisticians, programmers, and data managers should not be spending so much time stitching together datasets, formatting outputs, resolving handoff issues, and repeating the same cleanup and QC loops across disconnected tools. Astraea keeps experts in control of the critical decisions while dramatically reducing the operational burden around them. We are starting with the workflows that matter most in trial analysis and reporting: SDTM generation, ADaM generation, statistical programming workflows, TFL generation, and the QC and revision cycles needed to get outputs ready for delivery. Over time, Astraea is building toward a full end-to-end system for modern clinical trial data execution in regulated environments.

Klarify handles every job a therapist does other than the therapy itself, from clinical notes and treatment plans to insurance claims and finding new clients. Therapists hold the world together. They also run businesses, file insurance claims, write letters, fill forms, supervise new grads, and do hours of paperwork every night. Practice management software has existed for decades. It records what therapists do. It can't actually do any of it. Klara is the AI at the heart of Klarify. She handles notes, treatment plans, clinical letters, insurance claims, between-session resources, supervision prep, and finding new clients. Nearly 6,000 therapists use Klarify today. Our mission is to empower therapists, not replace them. So they can focus on the one thing only a human can do. Be present with their client.

Juno is an AI personal health assistant for the 1B+ people living with chronic illness. Juno builds a longitudinal health profile from conversations, biometrics, and medical history to identify patterns behind symptoms and provide tailored guidance. Isaac and Marshall started building Juno after growing up with chronic conditions and spending years trying to understand their symptoms. Like millions of others, they waited months for appointments and struggled to explain complex medical history in 15 minutes. As a result, key signals are missed, contributing to an average diagnosis time of 7.6 years. Even after receiving a diagnosis, patients are often left without a clear treatment plan and have to manage their condition alone. Many use AI chatbots for support, but without context on their medical history or symptom progression, they receive generic advice that is rarely actionable. Juno solves this by building a continuous, structured health profile for each user and connecting this fragmented health information. We spent the last year conducting research at Oxford and UCL to build our proprietary engagement layer for daily conversations, allowing Juno to ask the right questions at the right time and understand each user's health better than anyone else ever could. We launched in October and are already at $600k in annual run rate, supporting 50,000+ patients globally. We’re building a future where everyone has a private clinical specialist in their pocket, 24/7.

We turn medical records into personalized videos walking patients through onboarding, adherence, and recovery. The engagement data we collect builds our AI-native patient engagement platform for pharma, hospitals, medical devices, and private clinics, so they can stop chasing the patient and spend more time caring for them.

Harbor is a new, AI-enabled system of record for clinical trial data that replaces legacy electronic data capture (EDC) systems. Today, medical device and pharma companies spend months setting up custom EDCs that research sites then spend hours per subject per day entering data into. With Harbor, the EDC is spun up simply by reading your clinical trial protocol and research sites upload raw source documents into the platform, skipping the tedious and error-prone data entry process altogether. EDCs haven’t fundamentally changed since the 1990s. They are passive, regulatory compliant data bins that cause massive trial delays, coordinator burnout, and weeks of back-and-forth to resolve data errors. Because of this, data management currently consumes ~30% of total clinical trial budgets. With LLM and document extraction capabilities finally reaching the accuracy, reliability, and traceability required in high-risk domains, Harbor is redefining the way data is collected and monitored in clinical trials, all while remaining fully GCP- and 21 CFR Part 11 compliant. After months of building our initial product, our platform is now live with its first few clinical studies. For our largest customer and their 1600 subject randomized trial, we were able to use our internal tools to get their study database configured in just one week, which was ten times faster than legacy EDC vendors quoted. We built Harbor because we lived through this problem. Albert spent four years in clinical trials and regulatory strategy for a medical device startup, spending weeks at clinical sites watching coordinators battle legacy software firsthand. Nate brings the technical firepower, having built scalable software at Google and Ramp and as employee #1 at a previous YC startup.

Kaigo Health provides an AI-powered outpatient care management platform that automates and scales remote care management for Medicare patients including post-discharge followups, ongoing check-ins, and monitoring. Using phone calls as an age-friendly interface, we aggregate patient responses, voice biomarkers, and remote patient monitoring data for powerful preventative and proactive healthcare.

Norra helps nursing facilities manage equipment operations. Every year, ~$80 billion are spent on medical equipment like beds, concentrators, and wheelchairs. Nursing facilities continue to operate with zero visibility which leads to $15 billion in equipment waste annually. We use physical trackers and AI agents to eliminate this.

We deliver high-quality, cost-effective healthcare to employees through text. Employers cut 10–20% of healthcare spend. Employees get concierge care that improves outcomes. Our AI agents analyze clinical data to identify care needs. We treat common conditions through our integrated virtual clinic. For more complex care, our agents find the best in-network providers using millions of price and quality data points, and handle end-to-end appointment booking.

Nori is a concierge-level AI health coach in your pocket. It takes all of your health data—Apple Health, medical records, wearables, everything—and boils it down into a personalized daily plan. Users love it: “It's truly one of the best apps and I check it first every day. Since using Nori, I've been limiting devices in bed and eating earlier—and I'll be damned if it's not working... I started getting more deep sleep, my resting HR dropped to 43, my recovery improved.”—Jen, Nori user"

TakeCareOS is an AI-first operating system for care agencies. Our platform consolidates every function an agency runs on — rostering, shifts, CRM, care notes, messaging, invoicing, timesheets, and compliance — into one place, with AI agents that automate the admin work coordinators currently do by hand. Care agencies are one of the most operationally complex small businesses to run, yet most are still managed across a patchwork of spreadsheets, WhatsApp group chats, shared drives, and physical forms. TakeCareOS replaces that fragmentation with a single, intelligent platform that lets agencies run efficiently and scale without adding headcount.

LunaBill is building AI Voice callers for healthcare billing teams. Insurance claim follow-up calls account for the 80% of the daily workload of a healthcare billing team, with each call averaging 30 minutes. Since our launch in July we are now at $764K in contracted ARR, of which $428K is live revenue and the rest will go live by January 2026. Our customers see a 10x increase in claims followed up per biller in the first week and we have converted 100% of pilots to paying customers. We have automated 50,000+ calls and signed partnerships with top healthcare leaders like UC health systems, Mayo, Experian Health and more. The founders have known each other for over a year. Suhail is a 2x founder, with 3+ years of experience building in healthcare including operating a medical billing company with 200+ healthcare clients. David founded Skiesoft, Taiwan’s biggest healthcare AI scribe company, used by 120k+ healthcare professionals. He also worked as a data scientist at UCSF, building models to audit medical-coding accuracy. Yash was a researcher at various hospital systems including Mayo Clinic.

Prosper builds AI phone agents for healthcare providers. Our agents automate manual, time-intensive workflows like patient scheduling, balance reminders, claims status checks, benefit verification, and prior authorizations. We integrate with 80+ EHRs, go live in 3 weeks, and offer a no-code interface for customization. Today, Prosper handles thousands of daily calls for dozens of providers, reducing costs by 50% and tripling productivity. We’re building the AI-first operating system for healthcare to eliminate the $200B lost to administrative overhead every year.

Parachute helps hospitals adopt AI safely and at scale. We vet AI tools that fill clinical gaps, run state-of-the-art evaluations, monitor every model for drift and compliance, and lock every decision in an immutable audit trail.

CareSwift is a real-time AI assistant built directly into ambulance reporting systems, guiding medics as they document care and instantly flagging errors. Crews complete accurate, compliant reports in under three minutes, cutting documentation time by 80 percent and helping agencies avoid insurance claim denials. Ambulance crews lose valuable time completing reports after each call. Even minor mistakes cause insurance claims to be rejected.

Adentris is an AI compliance copilot for hospitals and clinics. We are like Grammarly for doctors, finding and fixing mistakes that lead to denied insurance claims or patient lawsuits. The industry today spends $40B doing this manually.

Today, it takes months to understand how drugs perform in the real world, delaying safety insights and leaving patients exposed to unknown risks and benefits for far too long. Frekil turns that months-long process into minutes, with full auditability and scientific rigor. Frekil accelerates real world evidence (RWE) generation for life sciences companies on their own clinical data from months to minutes. It connects to fragmented clinical data (EHR, Claims, etc.) and lets teams run end-to-end studies from study design, cohort extraction to SAP, statistical analysis, and final reports.

Harbera helps clinic keep their doctors credentialed and compliant. Our AI software continuously monitors and proactively helps admin teams re-credential doctors, preventing denied claims, disruptions in patient care, and lost revenue caused by doctors falling out-of-network.

G LNK is an AI-powered platform simplifying how healthcare companies connect with the relevant medical professionals. Our proprietary matching and ranking models instantly identify the most qualified experts, accelerating drug development and commercialization. Designed with compliance at its core, G LNK ensures every connection meets strict regulatory and ethical standards—empowering companies to innovate faster with confidence.

YouShift uses AI to automate hospital shift scheduling, replacing legacy software and eliminating the need for full-time schedulers. And scheduling is just the beginning — we're building the future of healthcare workforce management.

Amby Health automates billing and quality reviews for ambulance agencies (EMS), replacing large back-office teams with AI. We analyze patient reports in seconds—not months—accurately coding claims and identifying liability and care risks while eliminating costly, error-prone manual processes.

Cenote builds AI sales reps for online health clinics and deploys them for abandoned-cart and win-back campaigns. Today, digital and telehealth clinics rely on generic text blasts or human follow-up for speed-to-lead and customer reactivation. Since the lead has often gone cold and the outreach isn’t personalized, conversion is frequently below 1%. Cenote’s AI agents reach out immediately, communicate on the patient’s preferred schedule, and operate across channels—dramatically increasing conversion rates and unlocking revenue that otherwise goes unrealized.

Mecha Health builds foundation models to automate x-ray analysis for radiologists. We take medical images and process them using proprietary models to produce accurate draft medical reports. Our first model was built in less than two months, and beat Microsoft, Google, and OpenAI on clinical accuracy metrics. On top of that, it’s two orders of magnitude smaller and trained with a quarter of the data. We are partnering with the largest privately owned radiology practice in the US and a multinational tele-radiology company to provide them with their own foundation model, enabling their radiologists to go from reading 1 scan per hour to 1 scan every 5 minutes. By charging on a per scan basis, x-ray report generation represents a 40B+ market opportunity.

We’re Toothy.ai. We’re building AI agents for dental practices that handle everything related to patient insurance. The average dental clinic spends over 160 hours a month on insurance tasks like verifying patient policies, billing, and claims processing. Our AI agents automate this entire workflow—including making insurance calls with voice AI—saving clinics time, reducing costs, and ensuring faster reimbursements.

HealthSpark empowers physical therapists (PTs) to start, run, and grow their own independent practices. Our AI-native “business-in-a-box” takes care of the administrative work—credentialing, insurance billing, patient onboarding, documentation, and scheduling—so PTs can focus on patient care, not paperwork.

FutureClinic is a platform that makes it easy for any doctor to open their own digital clinic. Our AI assistant takes a comprehensive medical history using an empathic chat or voice-based interface, uses sophisticated medical reasoning to narrow down likely diagnoses, and produces evidence-based treatment suggestions for each patient. Licensed doctors then review the text-based summaries of the cases our AI provides, and choose how to manage the patients. In this fashion, we're able to deliver end-to-end healthcare in a way that makes personalized, expert healthcare scalable to 8 billion people around the world.

Careforce builds AI Workers for healthcare orgs to take on coordination burden from staff and reduce time of care by autonomously identifying and outreaching patients (through phone, text, email, & mail) to schedule visits, book screenings, complete pre-post, and onboard. These agents require no integration, can navigate all tools, speak 29 languages, come with 50+ outreach scripts and have a remarkable 80% conversation-to-booking closing rate.

The mission of HYBRD is to take world-class coaching and make it universally available. Health data has never been more abundant. GPS watches track pace and heart rate, wearables monitor sleep and recovery, and voice logging has made it easier than ever to capture weightlifting and HYROX. And yet most athletes are still following static PDF plans they found online, or "adaptive" apps that fall apart the moment cross-training enters the picture. Existing tools feel disappointing because they don’t actually know your goals and constraints, so they can’t do anything meaningful with the data they collect. HYBRD can. We aggregate your wearable data, fill the gaps with a simple AI logger, and use that complete picture to build personalized training programs from the best coaches in the world, like Alex Viada, who coined the term "hybrid athlete." From there, the HYBRD agent keeps you on track, adjusting your schedule around weather, travel, and fatigue as you progress. Everything you'd get from a $500/month coach, at a 50x lower price. Founded in 2024 by WHOOP and AWS alumni, HYBRD is built by hybrid athletes. Join us for a workout every Monday morning in San Francisco and Boston.

The main document in a clinical trial is the study protocol. At large companies, floors of people use the protocol to create the study data collection forms, clinical database design, error checks, analysis code, and data transformation mappings. We use AI to automate the process of creating everything from the protocol, saving not only spend on headcount but also months of time which can translate to up to $27M in direct costs + lost revenue saved for a single phase 3 trial.

Planbase has everything health clinics need to manage their team in one place: capacity planning, employee scheduling, credentialing and payroll.

Dodo turns client communication into booked appointments, completed workflows, and predictive analytics, powering millions of client interactions annually for hundreds of clinics. Our multi-agent system autonomously runs scheduling, refills, intake, and follow-ups across calls and texts — integrating directly with clinic systems to cut communication overhead ~70% and act like a trained CSR 24/7.

Codes automates medical record retrieval. Today, documents are scattered across EHRs, providers, and faxes; we use AI to compile & analyze docs for law firms, providers, and more.

At Brighterway, we use AI to speed up the medical record review process in the Workers' Compensation Industry. Physicians and claims handlers spend hours reviewing thousands of pages of medical documents– our technology highlights the information that is most relevant to a doctor's specialty or a given injury, streamlining their review process and saving them time. Brighterway structures and deduplicates disorganized medical records (PDFs) and extracts the content that is medically relevant and related to a given claim, so they can focus on what matters most.

The American healthcare system is complicated. 88% of US adults cite difficulties navigating the healthcare system. The good news is patient advocacy became a covered benefit by Medicare in 2024. Understood Care matches Medicare patients with a healthcare personal assistant (known as a Patient Advocate) at little to no cost to the patient. Patient Advocates help patients patients access care - finding resources, helping fill out paperwork, and much more. Understood Care uses AI and healthcare expertise to deliver the highest quality patient advocacy to the 68 million Medicare patients in the US.

Burdensome documentation is the #2 reason causing burnout for physical therapists. More than half of all physical therapists have to write documentation in their free time without pay. up to 2 hours a day. Our AI Scribe listens, generate first draft of clinical documentation in minutes, and sync reviewed documentation to EMR in 2 seconds. With us, clinicians can finish documentation 70% faster and become happier.

All-in-one RTM platform designed for physical therapy and powered by AI

Clarion is building the most advanced AI communication layer for healthcare. Our AI agents handle the overwhelming volume of calls and messages that clinics face daily—from scheduling to billing to prescription refills—freeing staff to focus on patient care. We're an in-person company based in New York. Today, clinics miss 30-40% of inbound calls due to staffing shortages. We're solving this by automating complex workflows end-to-end, already serving tens of thousands of patients monthly across virtual care companies, health systems, and a $5B health insurance company. We've raised $5.4M from Accel, Y Combinator, Sequoia (scout), and healthcare founders from Ophelia, Medallion, and Counsel Health. Our founders bring both clinical and technical expertise—our CEO Ryan is a Stanford/Harvard-trained physician who was on the founding teams of Two Chairs and Ophelia, while our CTO Jeffrey built voice AI at Amazon Alexa and led AI/ML teams at Salesforce. Join us as we transform healthcare communication—creating a future where patients get faster resolutions and providers reclaim time for what matters most.

At Arini, we’re building the operating system for dental groups. Phones are the backbone of dental operations — 80% of appointments are still booked over the phone — yet practices miss 20–30% of inbound calls. That’s millions in lost revenue every month. Patient engagement is the biggest bottleneck to growth in dentistry, and we’ve built the most comprehensive AI-powered patient engagement suite in the industry. Arini manages calls, texts, and bookings. We’re going after a $220B, overlooked industry that still runs on legacy systems and outdated workflows. Arini is bringing AI to every part of the dental stack.

Scritch is building the leading AI systems for veterinary medicine, starting with voice agents that automate front-desk operations in veterinary practices.

Andy is AI software that completes documentation for nurses doing home visits. Our software saves $8B a year; Tiantian was previously a PM at Google’s healthcare business and Max was a staff engineer on the health team at Apple. Andy benefits nurses and the agencies that employ them. Agencies that use Andy see up to 45% more detailed charts, 2x greater nurse productivity, and timely submission (no more billing delays!) With Andy, clinicians get their evenings back. Home health is the fastest growing segment of healthcare, doubling to $251B by 2031. Combined with recent nursing shortages and burnout, we’re seeing not just urgency, but excitement and joy, around adopting AI for home health.

Over 80% of maternal mortalities were preventable with earlier intervention. Currently, doctors miss >50% of moms who have life-threatening complications and wait until labor to start doing manual risk assessments, at which point it's too late. Elythea's proprietary ML models catch life-threatening obstetric complications (like postpartum hemorrhage, preeclampsia/eclampsia, emergency c-section, preterm labor, and more) as soon as the first visit. We automatically analyze relevant demographic and clinical risk factors, flag high-risk patients, and provide evidence-based interventions, giving doctors months in advance to intervene and prevent complications from ever happening. Our global clinical studies have shown that we can catch 3x more complications than clinical judgment 10x sooner.

LifestyleRx delivers insurance-covered virtual care for Type 2 Diabetes reversal. Our doctors guide patients through lifestyle changes to reverse the underlying process of diabetes.

Fortuna is a one-stop solution that helps consumers navigate Medicaid end-to-end from eligibility and enrollment to renewing coverage. Our platform creates value as the middleware layer for the $800B Medicaid ecosystem.

Shasta Health builds AI agents to handle patient calls, verify insurance and automate admin tasks for healthcare clinics

Cair Health empowers billing companies, care management platforms, EHRs, offshore BPOs, provider groups, and specialty pharmacies with AI-driven RCM solutions. Our suite of AI Agents helps RCM teams streamline operations, reduce manual costs, and improve consistency—while maintaining full control over core workflows. Cair is trusted by 100+ practices across the country — including iconic VC-backed digital health startups, leading specialty EHRs, and some of the largest billing companies and BPOs Backed by Y Combinator, Foundation Capital, Soma Capital, Translink Capital & many others..

VetRec automates the process of taking clinical notes for veterinarians in a matter of seconds. Veterinarians should just review clinical notes, not spend time creating them. A visit with a pet is precious and 100% of the focus should be spent on the pet, not on notes. VetRec is the veterinarian's best friend.

Sohar Health is an AI-driven front-end RCM solution that transforms insurance verification processes for healthcare providers, enabling faster patient conversions and reducing administrative workloads. With a 95% automation rate, our API-first platform seamlessly integrates into existing workflows to provide real-time claim accuracy and eligibility checks. Key performance metrics showcase the power of our technology: Median latency of just 6 seconds, ensuring real-time eligibility; over 90% of checks returned within 30 seconds for increased patient conversion; 96% accuracy in identifying and verifying benefits details; Industry-leading 99% accuracy for eligibility determination; >90% carve-out detection rate, mitigating surprise billing risks; a 60% success rate with our Insurance Discovery API, helping identify coverage for self-pay patients. Our customers include outpatient clinics, specialty practices, and digital health platforms looking to streamline front-end claim management. By reducing errors and maximizing clean claim submissions, Sohar Health empowers healthcare organizations to convert and retain more patients, reduce operating costs, and increase their top-line revenue.

Healthtech-1 automates repetitive processes for healthcare systems. We’re starting with the world’s most famous: the NHS. We’re already live in over 1,400+ primary care practices. Based out of Raj's parents' Primary Care practice the Healthtech 1 team are systematically digitising the repetitive processes they experience everyday, saving thousands of hours of staff time. Why now? The UK's National Health Service (NHS) delivers free healthcare in 590 million patient contacts every year. Post-pandemic, Britain's most treasured institution is in crisis. Patient satisfaction is at 25 year low and 1/7 staff are applying for Non-NHS jobs fuelling an 11% recruitment gap. By digitising the 100s of repetitive processes in healthcare, Healthtech 1 will reverse the trend, and produce the world's most productive health care system.

We are rebuilding the core infrastructure behind corporate health insurance, everything from care navigation, analytics, claims, and more. Fully cloud-native and AI-first. We are eager to directly impact the health and savings of 60% of the American population.