Biometrics Startups funded by Y Combinator (YC) 2026

Play Health is building a perimenopause care platform to provide women and their providers with the tools they need to relieve symptoms fast. It is led by technical, second-time, YC-backed founders Andrea Mazzocchi, PhD and Ian Miller, with an exit and a unicorn between them. Over 30 million women in the U.S. are experiencing perimenopause symptoms, spending an estimated $15B+ annually on symptom management. Despite this most only receive generic solutions and struggle to find effective symptom relief. We're bringing evidence-based perimenopause care to women through partnerships with medical practices and employer and health benefits programs. Our platform integrates personalized symptom, medication, and lifestyle data to generate AI-powered insights and clinical protocols, enabling providers to deliver specialized care. Every clinical interaction enriches our longitudinal dataset allowing us to create better outcomes for patients, deeper insights for providers, and expand into women’s health broadly. This also enables us to partner with pharma and biotech companies developing therapeutics and diagnostics for women's health.

PeakPath is a service that helps enterprises improve team performance and employee retention. We pair each employee with an online coach and use smart watch data to improve their physical and mental health.

REPROSENT is a patient-driven care system that harnesses patients' time to relieve overburdened medical teams. With an app that elevates the role of both patients and their loved ones, REPROSENT helps patients stay on track, capture previously untapped data about their lived experience, and receive timely triage that improves their health outcomes. By making crucial patient information actionable, REPROSENT enables doctors to focus their time on personalized treatment, transforming the way medical care is provided.

We are developing a new paradigm for consumer health tech wearables by replacing a 100lb optical instrument with an area of silicon smaller than a postage stamp.

Thalmic Labs is pioneering new ways of interacting with digital devices. With a mission to merge people and technology, the company is revolutionizing how we will interact with technology in the future. Its first product, the Myo™ armband, measures electrical activity in muscles to wirelessly control computers, phones and other digital technologies, resulting in seamless interaction between humans and devices. Founded in 2012 by three graduates of the University of Waterloo's mechatronics engineering program (Stephen Lake, Matthew Bailey, Aaron Grant), Thalmic Labs has grown to a world-leading team of engineers, researchers, and creators committed to building the future of wearable technology. Thalmic Labs has raised over $140M USD to date from investors including Spark Capital, Intel Capital, Y Combinator, and others.