E-commerce Startups funded by Y Combinator (YC) in Los Angeles 2026

September 2026

Browse 9 of the top E-commerce startups funded by Y Combinator. Headquartered in Los Angeles, these are some of the hottest and fastest-growing startups. This doesn't include all companies originally founded in Los Angeles or by founders from there.

We also have a Startup Directory where you can search through over 5,000 companies.

  • Whatnot
    Whatnot
    Y Combinator LogoW2020
    Active • 731 employees • Los Angeles
    Whatnot is the largest livestream shopping platform in the U.S., connecting buyers and sellers in real-time across any category – from collectibles like trading cards to comics, fashion, sneakers, and more.
    marketplace
    e-commerce
  • WANTD
    WANTD
    Y Combinator LogoW2022
    Active • 4 employees • Los Angeles
    WANTD is a D2C consumer marketplace for fashion and footwear brands to launch and sell product. We do the things Shopify is unable to do; we provide multiple channels to sell (e.g. live commerce, marketplace, auctions), influencer networks, and order fulfillment in a mobile-first experience. We solve the cold-start problem for brands and enable them to remain focused on product creation.
    e-commerce
    marketplace
  • Oda
    Oda
    Y Combinator LogoW2020
    Active • 9 employees • Los Angeles
    Oda is an AI agent for home design. Homebuyers and renters alike can use Oda to discover their interior design preferences, apply those preferences to their new home, and then find the best furniture, décor, and appliances aggregated from many different online retailers. Oda distributes its product to homebuyers and renters through partnerships with real estate companies and platforms. Real estate partners add Oda AI iFrames to their websites to showcase listed homes with AI-generated designs. Each AI iFrame is directly linked to an Oda board, allowing consumers to transition from an iFrame to Oda to further personalize the designs and create their dream home.
    computer-vision
    machine-learning
    ai-assistant
    e-commerce
  • FLOWER CO.
    FLOWER CO.
    Y Combinator LogoW2019
    Active • 30 employees • Los Angeles
    We sell weed on the internet. We're a vertically integrated legal cannabis company delivering next-day in Los Angeles, Long Beach, San Francisco, East Bay, Marin, Humboldt, Sacramento, and Vallejo. We're venture-backed and growing exponentially.
    cannabis
    e-commerce
  • Lucy Goods, Inc
    Lucy Goods, Inc
    Y Combinator LogoW2018
    Active • 7 employees • Los Angeles
    If it isn’t bad enough that smokers don’t realize the scientific facts about nicotine, most non-tobacco nicotine products are poorly designed and unappealing to use. The leading gum is sold like a pharmaceutical drug, with flavoring and packaging to match. Vapes provide a cumbersome, over-the-top experience — with use as tightly restricted as cigarette smoking itself, but more juvenile, conspicuous, and highly addictive. People want, and deserve, a better way. Therefore, we want to deliver nicotine users a superior experience, and at the same time give them a way to transition out of feeling dependent. In a better society, people wouldn’t carry around the sensation that they’re stuck with an involuntary habit. Our mission isn’t to encourage nicotine use among people who haven’t started. Unlike certain vapes or other products, ours isn’t the sort coveted by underage users on social media. Our mission is to alleviate the harm related to tobacco — first and foremost, by switching people away from the most harmful products. So, at Lucy, we take an evidence based view of nicotine. Nicotine’s pleasurable properties make it an inevitable part of modern society. Therefore, minimizing harm in all nicotine products is key, in addition to giving people products and strategies for cessation. We feel that, as 1,300 people are dying of tobacco related illnesses every day in the US, the most important and immediate step toward a better society is giving nicotine consumers products they enjoy using that will cause less harm. Our first product is designed to appeal to smokers and encourage them to switch. And, looking ahead, we hope to secure approval in the future as a clinically proven smoking cessation aid, while continuing to participate in the FDA’s public hearings around how NRTs are best regulated. Our goals are simple: because harm reduction is a better strategy around nicotine delivery than abstinence or prohibition, we want to help improve public health — and reduce its costs — through a superior pure nicotine product.
    e-commerce
    biotech
    3d-printed-foods
  • Flowspace
    Flowspace
    Y Combinator LogoS2017
    Active • 48 employees • Los Angeles
    Flowspace is a modern fulfillment provider that combines powerful technology with expert fulfillment operations to deliver seamless and scalable execution that moves with your business. Purpose-built for ecommerce and omnichannel fulfillment, Flowspace unifies order management (OMS), inventory management (IMS), network optimization, seamless integrations, EDI, and proprietary warehouse management (WMS) technology. With negotiated carrier rates, automated B2B packing, D2C kitting and bundling, and a self-service AI tool, Flowspace provides the flexibility and control modern brands need to operate efficiently at scale without adding operational headcount.
    e-commerce
    logistics
    supply-chain
  • Leon & George
    Leon & George
    Y Combinator LogoS2017
    Active • 10 employees • Los Angeles
    Léon & George is a California based ecommerce retailer, specializing in premium indoor and outdoor plants, luxury ceramics and lifestyle goods. Recognized for their streamlined local delivery service across California, custom-engineered packaging for nationwide shipping and commitment to exemplary quality, they have cultivated a vast following since the brand’s inception in 2016.
    e-commerce
  • Lumi
    Lumi
    Y Combinator LogoW2015
    Acquired • 67 employees • Los Angeles
    Lumi.com provides packaging and shipping supplies to online brands, from small businesses to leading ecommerce companies shipping millions of orders per month.
    e-commerce
    supply-chain