Y Combinator Startups in Boston that are currently hiring 2025

May 2025

Browse 10 of the top startups funded by Y Combinator. Headquartered in Boston, these are some of the hottest and fastest-growing startups. Their teams are well-funded and actively hiring.

We also have a Startup Directory where you can search through over 5,000 companies.

  • Apprentice Health
    Apprentice Health
    Y Combinator LogoS2018
    Active • 6 employees • Boston, MA, USA
    We deploy location beacons to track the movements of patients and doctors, measure the inefficiencies in the doctors’ workflows, and then give the hospitals targeted recommendations on how to improve.
    healthcare
  • Alpha Vantage
    Alpha Vantage
    Y Combinator LogoS2018
    Active • 8 employees • Boston, MA, USA
    Alpha Vantage provides enterprise-grade financial market data through a set of powerful and developer-friendly data APIs and spreadsheets. Whether you need traditional asset classes (e.g., stocks, ETFs, commodities), economic metrics, foreign exchange rates, cryptocurrencies, fundamental data or even technical indicators, Alpha Vantage is your one-stop shop for global market data delivered through REST APIs.
    artificial-intelligence
    developer-tools
    saas
    analytics
    api
  • Ascen
    Ascen
    Y Combinator LogoW2019
    Active • 17 employees • Boston, MA, USA
    Ascen is a back office platform and employer of record for staffing firms.
    saas
    b2b
    compliance
    hr-tech
  • Community Phone Company
    Community Phone Company
    Y Combinator LogoW2019
    Active • 70 employees • San Francisco, CA, USA
    Community Phone is building the best phone for communities in America. We are your hair salon’s business phone, how your auto-body shop texts you or gets appointments, your local government agency’s operations line, and your mom’s phone that she sometimes answers on her computer. We have more than 20,000 customers today, and are building the Square of phones. Our team is ~80 people strong, across 15 countries. We are growing quickly, backed by Y Combinator Accelerator and Y Combinator’s Continuity Fund. We are customer-obsessed to the core. When we had a major network outage, everyone from recruiters to engineers to marketers to customer support agents got on the phone with our customers. Our team exemplifies our purpose. Join us on our mission to make it as easy as possible for people and people at organizations in our communities to communicate.
    artificial-intelligence
    saas
    b2b
    customer-support
    telecommunications
  • Nextera Robotics
    Nextera Robotics
    Y Combinator LogoS2020
    Active • 15 employees • Boston, MA, USA
    Nextera Robotics is an AI-native Robotics and Industrial Automation company founded at MIT.
    artificial-intelligence
    autonomous-delivery
    deep-learning
    robotics
    construction
  • Nabla Bio
    Nabla Bio
    Y Combinator LogoS2020
    Active • 8 employees • Boston, MA, USA
    Our mission is to enable pharmaceutical and biotech companies to bring more antibody therapies to patients. Using AI and massively parallel experimentation, we design antibodies that precisely bind the disease target at the right location, while minimizing manufacturability and toxicity risks. We are a well-funded, revenue-generating, bilingual company of wet- and dry-lab scientists, and are founded by AI and protein design experts from Harvard University.
    ai-powered-drug-discovery
  • Reviving Mind
    Reviving Mind
    Y Combinator LogoW2022
    Active • 3 employees • Boston, MA, USA
    Navigating chronic illness is an isolating and lonely process which ultimately reduces medical adherence and adversely impacts outcomes. There are over 100 deadly chronic conditions as 1 out of 2 Americans is currently living with at least 1 chronic condition. The US healthcare system has over $1 trillion dollars in direct costs. Medical adherence rates for therapeutic programs and medicine are only 50% because patients feel lonely, isolated, and unsupported in their chronic illness journey. Reviving Mind is an in-network telehealth provider that improves clinical outcomes and program adherence for the senior medicare and medicare-advantage population that is plagued with loneliness and chronic illness. This is done through a novel and proprietary clinical program and technology platform that integrates virtual, private, curated, and professionally led groups that scale up to 8-patients with individualized and goal oriented lifestyle medicine coaching that is automated but managed by a licensed provider. Scaling rapidly across the United States.
    consumer-health-services
    digital-health
    healthcare
    telemedicine
  • FlyCode
    FlyCode
    Y Combinator LogoS2022
    Active • 7 employees • Boston, MA, USA
    FlyCode Dunning & Payment Management AI that helps subscription merchants maximize revenue. We reduce passive churn by managing payment failures intelligently. We’re Jake, Etai, and TD and we’re building FlyCode. TL;DR: If you sell SaaS or B2C subscriptions, we’re here to help you recover lost revenue due to failed payments and involuntary churn. ‘Involuntary’ or ‘Passive’ churn is a hidden Revenue Killer 💳 for Subscription Businesses ❌ THE PROBLEM: Recovering Failed Payments is Complex Involuntary churn refers to the loss of subscribers due to payment failures, not due to them actively canceling. While it is both possible and a worthwhile strategy to attempt to win back a customer during the cancellation process — involuntary churn is not intentional and in most cases, your customers aren’t even aware that their payment failed. 💰 Bottom line? Effective payment optimization does reduce involuntary churn and will increase ARR by as much as 5-10% FLYCODE SOLUTION 💡 FlyCode leverages ML and AI to provide Payment Optimization and smart payment retries to maximize subscription revenue and reduce churn. We apply a unique model tailored to each Merchant and their customers to ensure optimal results. ⚡️Automatically recover failed subscription payments and reduce passive churn ⚡️Use ML & AI based payment optimization to find the best time to charge your customers ⚡️ Improve customer experience by coordinating payment retries with customer emails/SMS 🛠️ We support OOTB + Custom Integrations for Merchants and White-Label for Platforms
    fintech
    payments
    e-commerce
    subscriptions
    ai
  • Sandbox Banking
    Y Combinator LogoW2017
    Acquired • 33 employees • Boston, MA, USA
    Sandbox Banking provides a low-code platform to quickly build and run banking integrations. Our software is literally a web application named Glyue, and it's typically used by banks, credit unions, and fintechs to connect banking systems. Glyue integrations are often web service APIs, batch ETL jobs, file/document transfer jobs, or event-driven pub/sub services (e.g. web hooks, Kafka streaming data pipelines).
    banking-as-a-service
    fintech
    b2b