Y Combinator Startups in Boston that are currently hiring 2026

May 2026

Browse 15 of the top startups funded by Y Combinator. Headquartered in Boston, these are some of the hottest and fastest-growing startups. Their teams are well-funded and actively hiring. This doesn't include all companies originally founded in Boston or by founders from there.

We also have a Startup Directory where you can search through over 5,000 companies.

  • Yuma AI
    Yuma AI
    Y Combinator LogoW2023
    Active • 26 employees • Boston, MA, USA
    ## What is Yuma AI? Yuma is automating customer support by providing an AI Support Agent orchestration platform. Yuma provides autonomous AI agents dedicated to customer service and e-commerce. We integrate directly with help desk software (Zendesk, Kustomer, Gorgias, etc.) and focus on helping large Shopify brands deal with their high volume of support requests. Top merchants using Yuma can automate up to 80% of their support tickets fully autonomously. ## Why do Shopify merchants need Yuma? There are thousands of large Shopify merchants around the world generating $10M+ a year. Most of them have taken over some niches and are great at what they do: selling their products. But they all have one thing in common: they all hate customer support. It's a burden for them and a huge source of cost, as they receive hundreds of requests per day. Some of them have dozens of support agents on staff, usually offshore, and the overall quality is still often pretty poor while staff turnover remains high. Those merchants have been promised automation for years but have always been disappointed by the outcome. As customers, we have all had to live through a terrible support automation experience before, so this is no secret, and everyone knows that the current state of the technology is quite bad. ## Yuma is solving this in a few ways: Yuma isn't just another RAG chatbot. Our platform provides autonomous AI agents dedicated to support and ecommerce. These agents are powered by knowledge, follow processes, and are managed by our in-house AI orchestration technology. This ensures safety, control, and quality at every step. We believe that to truly automate customer support, we must develop a platform that mimics the actions of a human support agent. That's exactly what we've been doing. Currently, our top merchants are automating 60% of their support tickets through Yuma. Yuma can fetch information from external services and take actions in other apps as needed to resolve each ticket. We are laser-focused on building the best AI support agent platform and aim to achieve 80% true automation in the next few months. ## Fun Fact Yuma got started by accident. This is my third YC startup after Socialcam (W12) and Triplebyte (S15). I released Yuma as a prototype for fun in mid-December 2022 and was overwhelmed with demo requests. That's when I knew I was onto something and had to turn this into a real company, once again.
    artificial-intelligence
    customer-support
    ai
    conversational-ai
    ai-assistant
  • Vector
    Vector
    Y Combinator LogoW2023
    Active • 20 employees • Boston, MA, USA
    B2B advertising is broken: poor targeting, wasted ad spend, bot traffic, and 3rd party-cookies. Vector helps marketers drive pipeline with contact-level targeting and revealing who's seeing your ads (even if they never convert).
    generative-ai
    saas
    b2b
    marketing
    enterprise
  • FlyCode
    FlyCode
    Y Combinator LogoS2022
    Active • 7 employees • Boston, MA, USA
    FlyCode helps subscription merchants maximize revenue. We reduce involuntary churn by managing payment failures intelligently. We’re Jake, Etai, and Tzachi and we’re building FlyCode. TL;DR: If you sell SaaS or B2C subscriptions, we’re here to help you recover lost revenue due to failed payments and involuntary churn. ‘Involuntary’ or ‘Passive’ churn is a hidden Revenue Killer 💳 for Subscription Businesses ❌ THE PROBLEM: Recovering Failed Payments is Complex Involuntary churn refers to the loss of subscribers due to payment failures, not due to them actively canceling. While it is both possible and a worthwhile strategy to attempt to win back a customer during the cancellation process — involuntary churn is not intentional and in most cases, your customers aren’t even aware that their payment failed. 💰 Bottom line? Effective payment optimization does reduce involuntary churn and will increase ARR by as much as 5-10% FLYCODE SOLUTION 💡 FlyCode leverages ML and AI to provide Payment Optimization and smart payment retries to maximize subscription revenue and reduce churn. We apply a unique model tailored to each Merchant and their customers to ensure optimal results. ⚡️Automatically recover failed subscription payments and reduce passive churn ⚡️Use ML & AI based payment optimization to find the best time to charge your customers ⚡️ Improve customer experience by coordinating payment retries with customer emails/SMS 🛠️ We support OOTB + Custom Integrations for Merchants and White-Label for Platforms
    artificial-intelligence
    fintech
    payments
    e-commerce
    subscriptions
  • KaiPod Learning
    KaiPod Learning
    Y Combinator LogoS2021
    Active • 27 employees • Boston, MA, USA
    KaiPod Learning is a national network of microschools bringing school choice to every community in America. We work with education entrepreneurs to start high-quality microschools to better serve students and their families. As more families stand up for choice in education and as more educators look for alternative career pathways, KaiPod Learning is helping bring microschools into the mainstream.
    education
    elearning
    consumer
  • Kodex
    Kodex
    Y Combinator LogoS2021
    Active • 30 employees • Boston, MA, USA
    Kodex makes it easy for companies to process, and respond to, subpoenas from governments around the world. Agencies, like the FBI, subpoena user data from customers like Coinbase, and thousands of other companies - without Kodex, companies largely rely on email, fax, and spreadsheets to manage them. Kodex is a SaaS tool that helps private sector companies manage relationships, workflows, and secure file transfer with government agencies who are seeking confidential information on a company's users. We streamline compliance operations, protect the privacy of their users, reduce error, and validate the legitimacy of government agents who are requesting information.
    govtech
    compliance
    legaltech
    regtech
  • SiPhox Health
    SiPhox Health
    Y Combinator LogoS2020
    Active • 63 employees • Burlington, MA, USA
    We are developing a new paradigm for consumer health tech wearables by replacing a 100lb optical instrument with an area of silicon smaller than a postage stamp.
    hard-tech
    biometrics
    nanosensors
    health-tech
    health-&-wellness
  • Nextera Robotics
    Nextera Robotics
    Y Combinator LogoS2020
    Active • 20 employees • Boston, MA, USA
    Nextera Robotics is an AI-native Robotics and Industrial Automation company founded at MIT.
    artificial-intelligence
    autonomous-delivery
    deep-learning
    robotics
    construction
  • PostEra
    PostEra
    Y Combinator LogoW2020
    Active • 40 employees • Boston, MA, USA
    PostEra is building a modern 21st century biopharma. We're using our advances in machine learning to accelerate Medicinal Chemistry and bring more cures to patients. PostEra advances small molecule programs through partnerships with biopharma while also advancing its own internal pipeline. We've raised $26M from top investors and closed $1Bn in AI partnerships, signing multi-year agreements with Amgen, Pfizer and the NIH. PostEra also launched and led the world's largest open-science drug discovery effort; COVID Moonshot.
    ai-powered-drug-discovery
    machine-learning
    covid-19
  • Upsolve
    Upsolve
    Y Combinator LogoW2019
    Active • 12 employees • Boston
    Upsolve is a tech-driven nonprofit that helps low-income Americans overcome debt and rebuild credit at scale. Upsolve was founded in Harvard Law School’s Access to Justice Lab in 2016. Since then, Upsolve has become the nation’s most visited nonprofit financial education site. Upsolve.org educates approximately 2.9 million people a year with 2,000 articles on an array of debt and credit topics. To date, Upsolve’s free DIY bankruptcy filing tool has been used by over 14,000 families to relieve over $600,000,000 in debt. Upsolve users are disproportionately Black and Brown with an average household income of $25,000. Upsolve is now launching a suite of AI tools to help low-income Americans resolve their financial distress earlier.
    fintech
    nonprofit
    legaltech
    consumer-finance
  • Alpha Vantage
    Alpha Vantage
    Y Combinator LogoS2018
    Active • 8 employees • Boston, MA, USA
    Alpha Vantage provides enterprise-grade financial market data through a set of powerful and developer-friendly data APIs and spreadsheets. Whether you need traditional asset classes (e.g., stocks, ETFs, commodities), economic metrics, foreign exchange rates, cryptocurrencies, fundamental data or even technical indicators, Alpha Vantage is your one-stop shop for global market data delivered through REST APIs.
    developer-tools
    saas
    analytics
    api
    ai
  • Apprentice Health
    Apprentice Health
    Y Combinator LogoS2018
    Active • 6 employees • Boston, MA, USA
    We deploy location beacons to track the movements of patients and doctors, measure the inefficiencies in the doctors’ workflows, and then give the hospitals targeted recommendations on how to improve.
    healthcare
  • Ascen
    Ascen
    Y Combinator LogoW2019
    Acquired • 17 employees • Boston, MA, USA
    Ascen is a back office platform and employer of record for staffing firms.
    saas
    b2b
    compliance
    hr-tech
  • Sandbox Banking
    Y Combinator LogoW2017
    Acquired • 33 employees • Boston, MA, USA
    Sandbox Banking provides a low-code platform to quickly build and run banking integrations. Our software is literally a web application named Glyue, and it's typically used by banks, credit unions, and fintechs to connect banking systems. Glyue integrations are often web service APIs, batch ETL jobs, file/document transfer jobs, or event-driven pub/sub services (e.g. web hooks, Kafka streaming data pipelines).
    banking-as-a-service
    fintech
    b2b
  • One Codex
    One Codex
    Y Combinator LogoS2014
    Acquired • 16 employees • Boston
    One Codex is a data platform for applied microbial genomics, enabling new and valuable applications in clinical diagnostics, food safety, and biosecurity. Acquired by Invitae (NVTA) in February 2021. Spun out as an independent company in September 2022.
    biotech
    diagnostics
    genomics