Y Combinator Startups in New York that are currently hiring 2026

We’re a passionate team of dreamers and builders, determined to liberate small businesses from the not-so-fun aspects of the job so that they can focus on what’s fun and important.

SmartAsset is an online destination for consumer-focused financial information and advice. Reaching approximately 59 million people each month (as of January 2024) through its educational content and personalized calculators and tools, SmartAsset's mission is to help people make smart financial decisions. Additionally, SmartAsset powers SmartAsset AMP, a national marketplace connecting consumers to financial advisors. Building on SmartAsset’s relationship with millions of investors, SmartAsset AMP connects financial advisors directly with prospects who meet their target client profile. Our algorithm matches consumers with up to three fiduciary financial advisors. In 2023, SmartAsset helped advisors close an estimated $34 billion.

Founded by former WorldQuant portfolio manager & head of event driven systematic strategies Jeremie Cohen, KelAI is building the autonomous alpha engine for hedge funds, traders and institutional investors. Investment teams now have more data, tools and compute than ever, but research still runs across siloed systems and inefficient workflows. KelAI turns that fragmented process into a compounding AI-native engine that continuously finds, tests and validates trading signals at a pace no human team can match.

Revion is building the operating system for Automotive Retail. Our first product helps Technicians automate administrative work, which drains 30-40% of their day. With Revion, Auto Retailers can service more vehicles and drive more high-margin Revenue.

CellType is building an agentic drug company. AI agents that run the full drug discovery pipeline on top of biological foundation models that simulate human biology. Our core technology, developed with Google DeepMind, has already discovered and validated a new cancer treatment signal. We’re working with Top 10 pharma.

Launch crypto deposits in minutes. Unifold is a developer-first API + SDK that makes it easy for any app to accept on-chain deposits – across any chain and token – with less than 10 lines of code. We handle the full deposit flow so teams can ship faster and give users a smooth experience that actually works. If you’re building a consumer-facing on-chain product and want best-in-class deposits (or want to support more chains fast), we’d love to work with you.

Wayco is building a unified data intelligence layer for medical treatment of legal cases. From the first intake to instant settlement.

Maywood is the first finance-compliant proactive AI that runs 24/7, working across your network, pipeline, and active processes, running constantly in the background and surfacing things you'd otherwise miss. It tracks relationships and sector context to flag when a target is gearing up for a process (and drafts the outreach in your voice), watches network activity across LinkedIn, news, and conference follow-ups, and surfaces where active processes stand, including what's at risk since you last looked. It also auto-updates CRMs and trackers and creates meeting briefs that includes relationship history, recent activity, deal context, external research, talking points that can pull from internal and external data sources. Dealmakers interact with it over email, Teams, or the platform itself.

It takes 500,000 days of office work to bring a drug to market. We want to make it 5. To get there, we need agents doing most of the work. Today, our research agent is the best way to know what the FDA thinks. Users ask a question and get an answer backed by up to 1,000 documents, where each statement has a citation. It’s the best because we have the best retrieval engine. We’ve tuned it on our life science-specific dataset, and we find what others miss. As more teams use Rhizome, we gain more data on what regulatory professionals actually need, which makes retrieval even better. This flywheel is how we become the retrieval engine that powers all human and agent work in life sciences. Chetan started his career as a research engineer, but quickly realized he enjoyed building more than research. He joined EvolutionaryScale as their sole founding product engineer, launching their developer-scientist platform and scaling to tens of thousands of users and billions of API calls. He was also #16 at Instabase helping banks with document processing, closing $7m as the technical closer. Agents can do magical things today, but most in life sciences only use them to edit emails. Agents are missing the context they need to 100x the number of drugs we can bring to market. Rhizome AI is focused on that critical problem.

Mantis is a digital twin company that combines LLMs with high-fidelity physics simulations in order to convert rare and difficult-to-access human behavior data into predictive models.

Autonomous is a superintelligent financial advisor at 0% advisory fees. Today, managing your money means one of two bad options: DIY your money: You end up with accounts everywhere (401k, IRAs, brokerage, crypto, savings, equity, secondaries). Your spreadsheet is always wrong. You make expensive mistakes because this isn't your full-time job. Hire a financial advisor: They'll manage your money and charge 1-2% of assets annually. Run that math over multiple decades and you're handing over half your net worth to fees. Neither path can economically deliver the sophisticated, personalized strategies the ultra-wealthy use to compound wealth: strategic tax-loss harvesting across individual securities, systematic risk management, portfolio-backed borrowing to defer capital gains, access to alternatives, etc. These aren't secret – they're just economically impossible to deliver at scale through traditional human advisors. Robos were supposed to fix this, but they were designed in a pre-AI world. In practice they just manage cookie-cutter portfolios. They don’t coordinate across your 401(k), taxable accounts, mortgage, equity, and cash flow, they don’t help with real decisions like job offers, windfalls, or concentrated stock, and they don’t deliver institutional strategies. That’s why, even after a decade plus, the biggest robos are still <$100B AUM while old-school advisors like Raymond James / Edward Jones sit on trillions. We’re doing for financial advising what Robinhood did for brokerages. Think of it as a full-stack, AI-native wealth strategist that brings billionaire-style playbooks to ordinary investors. Autonomous is built around a frontier-scale reasoning engine—an AI that perceives global events as they unfold, understanding their deeper implications for markets and and most importantly, how these events will impact your investments.

F2 is the AI platform for private markets investors. Purpose-built for private credit, private equity, and commercial banking, F2 accelerates diligence, underwriting, and portfolio monitoring, helping teams evaluate deals over 60% faster. F2 turns unstructured deal data into investment-grade analysis and polished memos in minutes. Unlike general-purpose AI, F2 is built with the domain expertise and depth to handle the most complex financial analysis. Already trusted across thousands of deals, F2 makes collaboration easy and retains historical context, so past work compounds into future wins. Headquartered in New York City, F2 is backed by leading investors including NFX, Left Lane Capital, and Y Combinator.

DiligenceSquared delivers AI-powered market due diligence for investment decisions - like the $500k McKinsey reports, but automated, auditable, and at a fraction of the cost. When Private Equity funds evaluate deals, they pay firms like McKinsey, BCG, and Bain $500K-$1M for market due diligence. The process takes weeks, and the output is a static PowerPoint that's impossible to audit. A single large-cap PE fund can spend >$30M annually on this and the total market is $10B per year. Our AI agents conduct expert interviews and synthesize insights with every claim linked to source transcripts. No black box, no "trust me" slides, and no 10x mark-up for human labor. Frederik bought these reports as a Principal at Blackstone. Soren sold them as a Principal at BCG. Harshil is a repeat founder and former Software Engineer at Google. We've seen both sides and know what matters in due diligence - and now we automate it. Our clients already include 8 leading private equity funds with over $2.4 trillion in combined AUM.

Coding agents made writing code fast. But 6 engineers in a room will probably still disagree on what needs to be built. Scott AI is a planning workspace where engineering teams align on what to build before their coding agents start building it.

If you are a trusts & estates attorney, RIA, fintech, or family office interested in Sava, reach us at founders@savahq.com

Overdrive Health offers AI powered medical billing services, helping providers get paid more money in less time. Our technology enables us to provide the best quality insurance and patient billing services for a fraction of the usual cost

Aspect helps creative teams consolidate 5 media tools into one platform. We provide everything a media team needs: file ingest, local file streaming, review and approval, sharing, and archiving. Aspect workspaces come with an agent that has complete understanding of your asset library including comments and revisions. Ask the agent to complete any task in the background: searching for files, setting up folder structures, labeling and organizing footage, and much more. Check out aspect.inc/use-cases to see how different media teams use Aspect to deliver content faster.

We deliver high-quality, cost-effective healthcare to employees through text. Employers cut 10–20% of healthcare spend. Employees get concierge care that improves outcomes. Our AI agents analyze clinical data to identify care needs. We treat common conditions through our integrated virtual clinic. For more complex care, our agents find the best in-network providers using millions of price and quality data points, and handle end-to-end appointment booking.

Structured AI is building the AI workforce for construction design engineering, starting with AI agents that perform quality control on technical documents and drawings. Our agents learn your standards, apply the right building codes, and automatically review your drawings, so you see fewer clashes, fewer inconsistencies, and fewer costly RFIs and change orders. ⚙️ Automates QA/QC across mechanical, electrical, structural and more 🧩 Used by multi-disciplinary design firms to deliver projects faster with less risk 🚀 Mission: Free engineers to focus on creative design, not repetitive admin

We research how the world gets encoded for agents, and build the interfaces they transact through. Our latest work is OneStop — a unified market for AI.

Prosper builds AI phone agents for healthcare providers. Our agents automate manual, time-intensive workflows like patient scheduling, balance reminders, claims status checks, benefit verification, and prior authorizations. We integrate with 80+ EHRs, go live in 3 weeks, and offer a no-code interface for customization. Today, Prosper handles thousands of daily calls for dozens of providers, reducing costs by 50% and tripling productivity. We’re building the AI-first operating system for healthcare to eliminate the $200B lost to administrative overhead every year.

The domain specific AI for claims that gives leading insurers clarity and speed on the most complex claims

Fleetline is building the first complete-context algorithmic load planner for mid to large-sized trucking fleets. Today’s dispatchers face an overwhelming task: balancing regulations, customer demands, live fleet data, and individual driver needs, all while coordinating across siloed tools and teams. Mistakes run rampant, and each mistake is thousands of dollars. Even the select fleets using algorithms that have fleet-wide context struggle: the outputs are rigid, hard to interpret, and are blind to real-world nuances like driver preferences and schedule exceptions. Fleetline solves this by combining advanced optimization with LLMs that can easily adapt algorithms to each fleet’s needs and capture driver-specific information. The result is smarter planning truly optimized for every fleet and its drivers.

AI for account management and customer success. Ambral has already been used to drive hundreds of millions of dollars in attributable expansion revenue at multi-billion dollar enterprises and top scale-ups. Ambral synthesizes signals from all customer activity and interactions into AI-powered models of every account. It pinpoints who needs attention and why, and autonomously takes the best next action to drive expansions, prevent churn, and ensure no customer slips through the cracks. Team: Sam (CEO): 2x founder. Led AI at Everlywell and early PM at Wonder (now valued at $7bn). Lived the pain of losing customer intimacy at scale and is obsessed with solving it. Jack (CTO): Ex-SpaceX Flight Software Special Projects, where he developed telemetry routing and analysis systems for the most complex machines ever created. He’s now doing the same for the complexities of customer relationships.

IronLedger automates property accounting for property managers, developers and contractors, starting with accounts payable. We eliminate more than $70K of accounting costs annually for over 50K multifamily units. https://www.ironledger.ai/

Locata is an AI referral management platform for Primary Care. We deploy AI agents to automate every step of the referral process that back-office staff face daily, from submitting prior authorizations to broadcasting updates and following up with patients. This frees up staff to focus on patient care. Primary care back-offices are severely understaffed and overburdened by administrative work associated with referrals. Additionally, patients suffer navigating the complex referral process, which can have disastrous health effects if they don’t get the care they need. These factors point to a glaring gap in the system—where out of over 100 million specialist referrals issued annually in the US, only half are actually completed. Locata is tackling this problem head-on, saving administrative staff hours each week and ensuring that the referral process goes as smoothly as possible for patients and their providers. Alejandro and Josh met at Stanford where they graduated with BS degrees in Computer Science. Alejandro was a senior software engineer at Meta’s Reality Labs where he led development of several AI features for wearable products and prior to that conducted AI research at Stanford Medicine. Josh graduated with a masters in Computer Science, specializing in AI, before working as a software engineer at Google where he developed AI products that served over 1 billion users. Within two weeks of building our product, we signed a major regional health center and have saved them over 100 hours of work in our first month live.

Pangolin is an open-source, identity-based remote access platform built on WireGuard that enables secure, seamless connectivity to private and public resources.

Interfere is the experience layer for modern product teams. Detect, triage, and fix bugs automatically – no human required. Interfere finds issues in your app, understands what's happening, and owns resolution from first signal to production.

CareSwift is a real-time AI assistant built directly into ambulance reporting systems, guiding medics as they document care and instantly flagging errors. Crews complete accurate, compliant reports in under three minutes, cutting documentation time by 80 percent and helping agencies avoid insurance claim denials. Ambulance crews lose valuable time completing reports after each call. Even minor mistakes cause insurance claims to be rejected.

Photonium is building software to automate optical system design. We supercharge optics experts with intelligent tooling to reduce costs and deliver faster. We handle the full design stack — from optimization, verification, sourcing, to prototyping — for AR/VR, quantum, biotech, metrology/chip fab, LiDAR, and more.

Atlog creates voice agents with built-in compliance. Companies use Atlog to automate their calls and texts without worrying about getting sued.

Teach robots new skills through natural language and run reliably in production in minutes. Mbodi combines generative AI and agent orchestration, turning everyday language and quick demos into precise, reliable robot actions for industrial automation.

Acolite is an AI-powered insurance brokerage purpose-built for the construction industry. We combine modern technology with dedicated, licensed brokers to help contractors get the right coverage faster and at better rates than traditional brokerages can offer.

We're building an AI powered platform for engineers that are building new robots and machines. We allow users to invent and modify machine designs in a matter of minutes, not years. Ayna and Andy, the co-founders, met during their time at Harvard and started this in 2024 as their programs were wrapping up. We're commercializing 10+ years research done by our team at Harvard and MIT on this space. Our team wrote the very first papers on applying GenAI and optimization algorithms to compose robots from parts and applying computational design to fine tune machine designs. We're bringing in our deep knowledge of modifying equipment and integrating it into factories keenly understanding what makes hardware hard. We take in parts under consideration, constraints and tasks at hand and our algorithm formulates and fine tunes from 100s of possible design options. All in a few clicks, so engineers can push hardware to market faster and companies can benefit from the inventions being done by their R&D teams. We already have two paying customers in the OEM and system integrator spaces. We are venture backed and supported by a GBP 2.5MM grant by ARIA, the UK Government's invention agency.

Post-acute care loses billions to broken revenue infrastructure. Claim Health prevents it. We catch denials before they happen, automate the work drowning ops teams, and connect every step from referral to cash so agencies can scale without adding headcount. Kevin and JJ bring nearly a decade of experience building and scaling healthtech companies across different segments. Post-acute care is a $400B market with over $20B in annual revenue leakage due to broken revenue infrastructure. Claim Health is fixing that.

Ralo is the first AI-native mortgage broker. We use AI to remove layers of overhead and pass the savings back to borrowers. Our customers get rates more than half a point below the national average, save tens of thousands of dollars over the life of their loan.

Auctor brings alignment and intelligence to software implementation, enabling every project to deliver its intended value with clarity and precision.

Avallon automates insurance claims operations with AI agents that handle routine calls and documents processing.

First regulated exchange for compute

Law enforcement is drowning in data. Closure helps search it to solve crime. - Hiring: UX, Engineering, AI, Ops, Business Development - Supporting: law enforcement throughout the country - Expanding: Local, state, and federal law enforcement.

YouShift uses AI to automate hospital shift scheduling, replacing legacy software and eliminating the need for full-time schedulers. And scheduling is just the beginning — we're building the future of healthcare workforce management.

Artifact is a collaborative IDE for hardware engineers - accelerating every step in the engineering lifecycle: Design → Procurement → Manufacturing → Integration → Test → Sustainment We've raised $3.5M to build an integrated, verifiable AI copilot with an intuitive UI that reflects how hardware actually gets built. Every artifact is auto-generated and traceable to a single-source of truth. We believe hardware engineering should be rigorous, deliberate, and system-aware. We work directly with customers solving the world's hardest technical problems to modernize how complex hardware is engineered. If you're interested, send your resume & contact info to: careers@artifact.engineer

Trata is an AI-powered research desk for hedge funds. We use agents to interview hedge fund analysts, write investment research, and distribute this through a subscription.

The student information system (SIS) is the core system of record in every K-12 school. It tracks students, attendance, grades, schedules, staff, and more - kind of like the ERP for schools. Legacy SIS providers do just about that, and not much more. School districts layer dozens of tools on top of their SIS to fill in the gaps. Scout is an AI-powered student information system that automates school- and district-wide busywork, from day-to-day operations like attendance tracking to annual compliance reports. Our mission is to help school districts run like high-performing organizations, enabling them to provide high-quality, personalized instruction to every student.

Karsa is a stablecoin neobank for over 100M people in emerging markets. We enable people to buy dollar-denominated stablecoins, save money in US bank accounts, and spend anywhere with a Visa card.

Misprint is an all-in-one marketplace that solves the biggest pain point in the collectibles world: opaque pricing. Collectors, investors, and hobbyists currently rely on scattered data from auction houses, online forums, and reseller platforms, making it difficult to know the true value of their items. Misprint streamlines the process by combining accurate pricing analytics with a seamless buy/sell marketplace, making it easier than ever to understand and monetize collectible assets. Existing marketplaces lack robust, real-time analytics because accurate valuations require deep expertise in both the collectibles domain and advanced pricing algorithms. Misprint’s unique blend of insider trading card knowledge and machine learning allows us to fill this gap. Building these pricing models requires extensive data infrastructure, deep domain expertise, and cutting-edge ML. Recent surges in the trading card market show that collectors crave transparent valuations. The global collectibles market is worth tens of billions of dollars. Eva has experienced the scale of this industry firsthand, generating $500k ARR within three months of taking her Pokemon card-selling side hustle full-time. With additional segments like sports cards, comics, and emerging collectible categories, the growth runway is immense. Co-founders Eva and Jon have been best friends since Exeter, combining finance expertise, a passion for collectibles, and mathematical rigor. By merging Goldman Sachs-level financial analytics with top-tier mathematical talent, Misprint is uniquely positioned to become the go-to platform for fair, transparent pricing in the collectibles space.

E-waste recycling facilities spend most of their time and effort sifting through discarded electronics, searching for valuable devices, refurbishing them, and reselling them in second-hand markets. Our first product is an AI-enabled robotic system that integrates with these facilities to assess and refurbish hundreds of laptops a day without any human intervention. The system tests laptops, wipes their hard drives, photographs them, and posts them on online marketplaces for resale, regardless of model, manufacturer, or operating system.

Kilvin is an AI-native agency that builds custom software solutions for non-technical teams. With AI, the future of software is democratized. Every team deserves tools built exactly for them, not off-the-shelf SaaS products they need to adapt to. Kilvin makes it a reality, delivering a private, secure workspace of custom applications, built around your workflows and ready in days, not months. No engineers needed on your side. Just software that fits exactly how you work.

Keye is an AI software that lets private equity firms do due diligence for acquisitions faster and more accurately. Our customers can evaluate 10x more deals and fund better companies which leads directly to better returns/more alpha. -- Our system is the first of its kind to instantly generate complex, comprehensive data packs from raw data in any format, directly from the data room. This enables investors to gain an 80% understanding of a potential deal within moments, empowering them to say No to a deal earlier in the process and focus on high-potential opportunities. Traditionally, creating these detailed data packs—like cohort or retention analyses and customer roll-forwards—takes weeks, during which critical details may be overlooked, potentially costing funds millions in missed insights and poor decisions. -- Keye combines cutting-edge AI with deep private equity expertise to deliver powerful, multi-layered insights that go far beyond the simple summarizers and search functions offered by other tools. Our platform dives deep into both quantitative and qualitative due diligence data, offering high-impact analytics crafted specifically for private equity workflows. This isn’t just automation—it’s a purpose-built solution that uncovers actionable insights, fueling smarter decisions and driving true alpha.