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Promakhos Therapeutics

Promakhos Therapeutics

Y Combinator LogoS21ActiveTherapeutics

A therapeutics platform for curing inflammatory disorders

We are building a platform of bacterial molecules to awaken our body’s innate ability to control inflammation and heal. Our first indication is Crohn’s Disease, which affects over 500,000 Americans at an annual cost of $10B. After Crohn's disease, we are going for type 1 Diabetes and Multiple Sclerosis.

Promakhos Therapeutics
Founded:2021
Team Size:2
Location:Boston

Active Founders

Katerina Chatzi

I believe we can discover unexpected things that can transform our lives. I have lived and performed research in 4 countries and 2 continents. Previously I was a postdoc at Harvard. I founded Promakhos because I think we have given to “autoimmune” diseases a grossly misleading name and we treat them in a primitive way. Promakhos means the first to enter a battle. In ancient Greece Promakhos was the strongest to put in the front line of an army so that they will not even have to start a battle.

Jasper Edgar Neggers

In 2009, Jasper built a web-shop in the Netherlands. He then received a BSc, MSc and PhD in Biomedical Sciences from KU Leuven (Belgium). He pioneered the use of XPO1 inhibitors for treating cancer and invented a CRISPR-directed evolution technology for drug target deconvolution. Jasper then joined the Dana-Farber Cancer Institute and Broad Institute of MIT and Harvard to identify and validate new drug targets for gastrointestinal cancers. Now, he is developing drugs for chronic inflammation.

Jasper Edgar Neggers
Jasper Edgar Neggers
Promakhos Therapeutics