Thesis

Autonomous AI research

Jobs at Thesis

San Francisco, CA, US
$120K - $170K
0.75% - 2.00%
Any (new grads ok)

Why you should join Thesis

Artificial intelligence has solved some of humanity’s greatest mysteries, from protein folding to forecasting chaotic weather systems. Thesis is an AI research lab automating the process of AI R&D itself.

Today, neo labs applying AI to materials discovery, robotics, drug discovery, climate science, and beyond must build their own frontier AI infrastructure from scratch. They depend on fragmented tools, handcrafted pipelines, and human intuition to make progress.

Thesis gives them an instant, autonomous frontier AI lab. It transforms AI R&D into a hill-climbing machine capable of searching a vast combinatorial space of hypotheses, experiments, and evaluations. By using the outcome of every experiment to optimize the next, Thesis creates a loop of recursive self-improvement: turning machine learning research into a compounding system rather than a sequence of manual attempts.

Our mission is to put these systems into the hands of labs doing groundbreaking work, promoting them to the absolute frontier of science and engineering. The breakthroughs that define our generation will come from human research directives amplified by autonomous AI R&D.

We hire exceptional individuals, the underrated and the dauntless, to invent the future of AI research.

Thesis
Founded:2025
Batch:F25
Team Size:3
Status:
Active
Location:San Francisco
Founders
Luigi Charles
Luigi Charles
Founder
Sergio Charles
Sergio Charles
Co-Founder & CEO