Personalized drug discovery for blood cancer.
Are you looking for a mission driven company where your work will directly impact human lives? Do you have a passion for scientific data and broad experience writing web applications? Do you think that cancer treatment should be personalized and want to build software to accelerate that reality?
Notable Labs is a precision medicine company that has a translational drug discovery platform focused on identifying therapeutic options for relapsed and refractory cancer patients.
Our clinical research lab helps oncologists identify personalized combinations of existing FDA-approved treatments for patients. We’ve developed a high throughput robotic flow cytometry lab platform that screens thousands of FDA-approved drug combinations against the patient’s own cancer cells to help predict safer and more effective cancer treatments. Our lab has completed initial feasibility studies with clinicians in relapsed Acute Myeloid Leukemia & Myelodysplastic Syndrome, with an 84% predictive rate. Focusing on individual patients and existing treatments, we’re working to discover novel uses of drugs and defining mechanisms underlying cancer progression and drug resistance.
Our research and development platform extends our clinical research to drug discovery, testing novel compounds with primary patient samples for pharmaceutical and biotechnology companies. Using our automated, high-throughput, multi-parametric drug screening research platform, industry partners can assay the biological impact of novel compounds on primary cells in a physiologically relevant environment. This helps our partners stratify patients by their predicted responsiveness, increasing the probability of successful clinical development. We are actively partnering with pharmaceutical companies that have preclinical and clinical stage drug pipelines in Acute Myeloid Leukemia, Myelodysplastic Syndrome, or related hematological malignancies to profile experimental drug activity in patient samples.
Our investors include Builders Venture Capital, Founders Fund, First Round Capital, Y Combinator, several prominent angels and seed-stage funds, and Accelerate Brain Cancer Cure, a venture philanthropy firm founded by Steve Case. We have offices and a laboratory in San Francisco’s SoMa district.
At Notable Labs we value diversity and are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Notable Labs is a mission-driven precision medicine startup building a translational drug discovery platform to identify treatment options for blood cancer patients.