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General Astronautics

The Space Robotics Company

Robots for microgravity research and manufacturing.
Active Founders
Bram Schork
Bram Schork
Co-Founder & CEO
Bram is a Caltech mechanical engineer who founded General Astronautics after building hardware reliability systems for SpaceX's Starlink Lasers, shipping industrial autonomous robots, and developing optical tracking systems at SBIR-funded startups. Microgravity unlocks better pharmaceuticals, semiconductors, and advanced materials. The bottleneck is labor, not science, and robots can solve that now.
Shibo Zhou
Shibo Zhou
Founder
Cofounder & CTO @ General Astronautics (W26) CS & Robotics @ CMU
Company Launches
General Astronautics — Robots for Space
See original launch post

Launch YC: General Astronautics — Robots for Space

TL;DR: General Astronautics builds autonomous robots for research and manufacturing in space. Microgravity unlocks better pharmaceuticals, purer semiconductors, and flawless optical fibers. The bottleneck was never the science, it was the labor to do it.

https://youtu.be/L5XrlbG-8ew

Advantage of Microgravity

Microgravity changes what's physically possible. Proteins crystallize with fewer defects, critical for drug development. Semiconductors and optical fibers form without the flaws that gravity creates. Pharma and tech companies are already investing in orbital research.

The Problem

But astronaut time is expensive, and there's not nearly enough of it. On ISS, NASA estimates crew time at $130K per hour. On commercial stations, it's more than three times that. Crews have to sleep, rotate home, and pick and choose which experiments to run. Most of the work that could happen in space simply doesn't.

The Solution

We're building robotic systems that handle laboratory work: pipetting, sample prep, plate handling, reagent mixing, with the precision and autonomy to operate without crew. The goal is simple: make microgravity research and manufacturing scalable, not bottlenecked by how many people you can put in orbit.

Our team comes from SpaceX, Caltech, and Carnegie Mellon. We've spent our careers on robotics, spacecraft systems, and the intersection of both. We started General Astronautics because the limiting factor in space was never the science, it is the capacity to do it at scale.

The Ask

If you have connections to pharma or biotech companies interested in space-based research, whether protein crystallization, biologics, cell culture, or silicon manufacturing, we'd love an intro.

Connect with us: founders@generalastro.com

X: https://x.com/GenAstronautics

LinkedIn: https://www.linkedin.com/company/generalastronautics

General Astronautics
Founded:2025
Batch:Winter 2026
Team Size:2
Status:
Active
Location:San Francisco
Primary Partner:Jon Xu