Primary Care Startups funded by Y Combinator (YC) 2026

Nest is a lab-agnostic, comprehensive solution for organizations to launch and implement large-scale genomic programs. The platform includes the ability to triage, consent, and counsel patients for genetic testing, provide EMR-integrated clinical decision support for providers managing patients with genetic results, and manage patients’ clinical needs across the continuum of care.

Okani is a low-cost wellness membership for the 50M Mexicans that spend 25B on healthcare out of pocket. We become patients' first point of contact with the healthcare system by providing digital primary care through chat and an app, then orchestrate the delivery of secondary healthcare with physicians, labs, pharmacies and clinics. We're founded by a team of 3 engineers and a doctor with a masters in clinical care. Pepe previously sold a startup to Cabify and ran engineering with Romario for Nubank's first international market.

Tuli health is turning all 11 000 independent pharmacies in the UK into diagnostic centers. Our software makes it easy for these pharmacies to sell and fulfill COVID-19 tests today and other diagnostic tests tomorrow. Instead of waiting for a long time or travelling a long distance to receive the tests, customers can now receive tests in their neighbourhood, with results guaranteed in 24 hours. Tuli Health was launched in June, had onboarded 147 pharmacies, performed over 7000 diagnostic tests, and helped pharmacies generate $1.3 million in incremental revenue per month. The vision is to make every local pharmacy into a diagnostic center powered by Tuli Health.

Rinse is building the One Medical for dental. Beautiful studios, easy to book same day appointments, and anxiety-free care focused on prevention, not the upsell.

PNOĒ enables health professionals to provide science-backed bio-optimization through breath analysis. For 100+ years, breath analysis (AKA metabolic testing, VO2max) has been the gold standard in anti-aging quantification, nutrition prescription, and evaluation of most critical systems, including the heart, lungs, cells, and nervous system. Until recently, it was only available in sophisticated clinics and regarded as the most valuable but underutilized assessment in medicine. PNOĒ changed that through the first easy-to-use clinical-grade breath analysis device, proprietary software package, and dedicated metabolic expert support. Through a non-invasive 10 min breath test, PNOĒ analyzes the human breath and prescribes a personalized nutrition, exercise, breathwork, and bio-optimization (i.e., red light therapy, hyperbaric chamber, IV therapy, etc.) program based on one’s biological limitations. 3,000+ health professionals trust PNOĒ because it personalizes the clients’ journey through their clinics, builds retention by quantifying progress, and enables the upsell of personalized nutrition and breathwork. All this without any effort, time commitment, or upfront cost. PNOĒ has been independently validated by Georgetown University, VA in Maryland, and Rutgers University and is trusted by leading institutions including Cenegenics, Dais Cove, MIT, UCLA, Pan Pacific, CLMBR, UCS, OURA, TONAL, Spartan Racing, and Paris Saint Germain.

Loop Health is a new type of healthcare provider in India combining high-quality primary care and insurance for employers. Employees get unlimited primary care visits at our asset-light clinics, alongside traditional hospitalization insurance. During YC, we grew from 0 to $85,000 ARR with 200% MoM growth. We serve 22 companies and 5500 members across Pune. Employers pay us $15/member/year and we make an additional $25 on prescriptions, lab tests, and hospitalization referrals. Our total gross margins are 70%. 200MM Indians are covered with employer-funded health insurance, representing a $8 billion dollar market opportunity, growing at 27% CAGR. Indian employers are dissatisfied with their health benefits today because insurance in India only covers hospital stays, not doctor visits – and only 8% of their employees will ever use the benefit in the year. With Loop, employers can offer a more engaging health benefit that includes doctor visits and telemedicine, alongside traditional hospital coverage, for about the same price. Because their employees have better access to doctors, we can also offer lower insurance premiums.

Circle Medical is a venture-backed Y-Combinator healthcare startup on a mission to bring quality, delightful primary care to everyone on the planet. Built by top-tier physicians, engineers, and designers, our medical practice and underlying technology have pioneered how people find and receive care. Our focus on building directly for our patients and providers to address serious care accessibility issues has enabled us to grow over 3X year-over-year. We’re now using our most recent round of funding from WELL Health, backed by Sir Li Ka-shing, to continue building out our hybrid in-clinic and telemedicine model across all fifty states. As we enter the hypergrowth phase, we are looking for deeply motivated team players who are driven to solve some of the biggest challenges in healthcare so that people can live longer and healthier lives. More about us can be found on our website!

Waiting rooms suck. Insurance and the paperwork are worse. We are a team of doctors, developers, lawyers, designers, and more working to try to fix it. Using our app, and soon the website, you can access medical care online right now and be done in 5 minutes. No insurance, video, or phone calls necessary and most visits are under $20. You can chat with your doctor anytime and anywhere. Our services are currently available in Arizona, California, Connecticut, Florida, Georgia, Illinois, Montana, New York, Ohio, Pennsylvania, Rhode Island, Virginia and Washington, but don't worry the rest of the country coming soon. Here are the medical services we offer so far: - Acne Diagnosis, Treatment, and Prevention - High Cholesterol (Lipid) Testing and Treatment - Start or Refill Birth Control - Urinary Tract Infection (UTI) Testing and Treatment - Vitamin D Screening and Treatment - Pre-Diabetes Screening and Referral - Hepatitis C Screening and Referral - Female Condom Prescription - Help Quitting Smoking - Find Out Your Blood Type We are adding new services every week, so if you don't see what you need let us know. We want HeyDoctor and our partner health systems to be your first stop for healthcare and be your personal medical record.