Enterprise Software Startups funded by Y Combinator (YC) 2026

Checkr builds people infrastructure for the future of work. And we believe everyone should have a fair chance to work. That's why we've designed a faster—and fairer—way to screen job seekers. For more information on our mission and products, visit https://checkr.com.

Unisson is building trusted AI subject-matter experts for teams that are responsible for customer deployments (technical customer success, implementation, sales engineering). Within 20 minutes, our agents learn to use any product and can be used by teams in Slack, text, or email. Our agents gather requirements and context from existing tools enabling them to handle complex tasks like customer health audits, onboarding, product administration, and custom integrations. With Unisson, customer-facing teams have 24/7 access to an AI SME, allowing them to scale and save thousands of hours.

REV1 automates the creation of manufacturing-ready 2D drawings from 3D CAD files. Mechanical engineers spend 25%+ of their time manually creating these drawings, a tedious but critical step for every manufactured part. REV1 reduces that process from hours to minutes, generating drawings with proper annotations and tolerancing so engineers can focus on design instead of documentation.

Oximy helps enterprises understand and manage AI usage across their workforce. Used by security, finance, and transformation teams to track adoption, control spend, and manage governance as AI scales.

Compresr provides an API that compresses LLM context without losing what matters. It’s a drop-in for agents and RAG that cuts token costs and improves accuracy.

Ritivel is an AI-native workspace for regulatory and medical writing teams at life sciences companies. Our AI agents draft CTDs, CSRs, INDs, and BLAs in minutes instead of weeks, helping drugs reach patients faster. Every month a drug is delayed from reaching the market costs pharma companies ~$45M in lost revenue and more importantly, delays treatment for thousands of patients who need it. Yet regulatory teams are stuck in a painful, months-long process: synthesizing thousands of pages of clinical data, hunting through SharePoint folders for the right documents, chasing colleagues for missing inputs, and manually drafting submissions. Ritivel deploys AI agents that transform how regulatory teams work. Our agents generate comprehensive first drafts directly in Microsoft Word, following FDA formatting requirements and pulling from your existing clinical data and prior submissions. Every data point includes citations linked back to the original source, so reviewers can verify with one click. Connected to SharePoint and Veeva, our agents automatically source the right documents. Integrated with Outlook, they handle reminder emails and follow-ups automatically. We're engineers who previously built AI copilots at Microsoft Research. After 50+ conversations with pharma professionals, we discovered the critical bottleneck in regulatory submissions and built Ritivel to solve it.

Our mission at 10x Science is to enable biopharmaceutical development to keep pace with AI-powered drug discovery. Thanks to AI, the front end of drug discovery is flooding the pipeline with new drug candidates. However, current solutions for drug development are unable to resolve drug complexity and cannot keep up with modern demand. Our platform is the unlock for this bottleneck. By applying modern AI to the development stage, specifically to protein characterization and quality assessment, we provide an end-to-end solution to dramatically speed up and scale up the preparation of candidates for the clinic. Our team is composed of Stanford University researchers from a Nobel Laureate's lab with 18+ years of collective domain expertise, 47+ scientific publications, and a 2x YC Founder. We move at the highest velocity and are positioned to lead the next-generation of modern AI drug development.

Chamber puts your AI infrastructure on autopilot. Our agentic AI enabled platform orchestrates, governs, and optimizes your AI infrastructure so teams can run ~50% more workloads on the same GPUs without manual intervention. It operates like an autonomous infrastructure team: continuously monitoring GPU clusters, forecasting demand, detecting unhealthy nodes, and reallocating resources in real time to where they create the most impact. Your ML teams move faster, infra waste drops, and GPU bottlenecks disappear.

Tensol lets you deploy and manage AI employees for your team - built on OpenClaw. Each AI employee runs 24/7 in its own isolated VM, has full context of your company, and can monitor Slack, track Sentry errors, update your CRM, and more. We handle the infrastructure, security, and deployment. Tensol also lets you create specialized AI employees for different jobs - engineering, sales, support, in a couple of minutes. You connect the tools your team already uses (Slack, GitHub, Sentry, HubSpot, Linear, Gmail, and more) with one-click integrations. Every action is logged with a full audit trail, credentials are injected at network-level, and each AI employee gets its own dedicated identity and sandboxed environment, with enterprise-grade security built-in.

We’re building AI agents that do on-call support for data-heavy industries like financial services and fintech, healthcare, and insurance. On-call engineers in these industries need to inspect data to debug production issues. We monitor both data and infrastructure for issues and use AI agents to debug and suggest fixes in minutes. Data is especially sensitive in regulated industries, so we offer on-prem deployments and hardware-backed secure environments that let agents safely use production data as context while debugging. Mitch and Shipra founded Corelayer after building data infrastructure together at Goldman Sachs, where they spent many late nights and weekends debugging systems that processed 100s of billions of rows a day.

Visibl is an AI platform that turns compute into chip design capacity. As chips grow more complex, adding engineers yields diminishing returns — coordination costs rise while progress slows. The bottleneck is no longer ideas, but execution throughput. Visibl turns compute into a teammate. Our platform ingests the full design context (code, specs, scripts, tool outputs) to decode ambiguous tool feedback into actionable steps. We validate changes and package decisions for review, resulting in safer changes, shorter iteration cycles, and fewer late surprises on the path to tapeout.

Human-assisted development should be for novel ideation, not routine maintenance, bug fixes or incremental updates. Approxima is bringing you that future with agents that can scope work, code, validate their fixes end-to-end in sandbox environments and merge to production. Book a demo: https://calendly.com/ashish-selvaraj/approxima

Constellation Space is building the autonomous infrastructure layer for the next generation of space networking. As satellite constellations rapidly scale from hundreds of nodes to tens of thousands, traditional ground-based orchestration fundamentally breaks down. ConstellationOS bridges this gap by providing zero-intervention network handoffs, predictive thermal load-balancing, and sub-second optical routing. Our founding team spent years building and operating satellite systems at SpaceX, Blue Origin, and NASA. We started Constellation to solve the problem we kept running into: reactive monitoring doesn't scale. We are building the sub-second routing protocols and hyperscale load-balancing infrastructure that will manage the future of off-world telecommunications and compute. hello@constellation-io.com

Avoice is an AI-native workspace for architecture firms that automates the operational work that takes time away from design. The platform uses AI agents that understand drawings, specifications, schedules, materials, codes, and past projects to automate documentation, coordination, QA/QC, and research. Today, firms using Avoice manage over $300M in active projects on the platform. Architecture is a massive market ($300B+) but a deeply underserved one: highly fragmented, dominated by small firms, and reliant on legacy tools that require heavy customization. AI creates a unique opportunity to deliver firm-specific automation at scale, and Avoice brings these workflows into become the operating system for architectural practice.

Nexus enables non-technical teams in large organizations to build production-ready AI agents without code.

Openroll is the AI-native operating system for compensation. Openroll gives companies a single system where compensation finally happens. Offers are sent instantly, budgets stay aligned automatically, promotions stay consistent, and salary decisions are made with confidence. Instead of fragmented tools, spreadsheets, and manual approvals, compensation runs end-to-end in one intelligent system used across the entire organization. Learn more at https://www.openroll.com

Adaptional is the first system of intelligence for insurance. Existing insurance systems organize work. Adaptional AI actually *does* the work. Our first product Underwriter AI pre processes every submission for an underwriter. AI extracts data from submission files, validates each data point using public sources, and summarizes risk using your underwriting guidelines.

Trace is a workflow orchestration platform that gives agents shared context across systems and lets teams build visual processes combining AI and humans. It automatically identifies which tasks can be AI-automated and which need human input, so non-technical teams build and run workflows without engineering involvement.

Riverbank is an ex-NSA and DoD team creating the first AI native offensive red team, starting with the $3B pentesting market. We blend AI agents with experienced human operators to find what traditional vulnerability scanners miss and break through organizational cyber defenses with swarms of AI agents.

Pangolin is an open-source, identity-based remote access platform built on WireGuard that enables secure, seamless connectivity to private and public resources.

Cyberdesk is the first self learning computer use agent for developers to automate desktop workflows. For example, one of our customers is building an AI agent for hospital patient intake, and they’re using us to automate an entire team of people manually clicking and typing into a desktop app to book appointments. We launched mid July, and our agent is already operating in production environments, creating appointments in electronic health record apps and processing files in legacy ERPs. We’ve built the first computer use agent that memorizes tasks and repeats them quickly while still adapting to unexpected changes on the screen. A good analogy is to how humans use computers: once we get used to an app, we use it much faster, while still adapting to random popups and crashes. This new paradigm for computer use will be needed by every company automating human workflows on computers. Mahmoud previously built robotic process automation solutions impacting 20K+ employees at a Fortune 100 company. He also built AI & ML solutions at Baylor College of Medicine Neuroscience & Texas Children's Hospital + co-published a paper at the Rice Networks Group. Alan is ex-NASA and previously dropped out to be the first founding engineer at a PearX startup. He is a second time founder, having previously built and scaled a consumer AI app to thousands of paying users. Computer-use agents will automate the $6T dollars spent on enterprise knowledge work and Cyberdesk will be the platform to power this. We’d love to talk with you! https://cal.com/mahmoud-al-madi-klrs5s/30min

Docket lets you write end-to-end tests in plain English and keeps them up to date automatically—powered by real user sessions.

Aravolta provides a single pane of glass software for data centers to increase uptime, reduce costs, and improve performance. A single utility node onboards every asset within an hour and detects hardware failures, hotspots, and other issues. It also generates reports on important metrics like Power Usage Effectiveness (PUE), energy metering, resource utilization, and much more.

We supercharge agents from Cursor to AgentKit with product and team-level context. Connect us once to where your internal data lives, then create secure data gateways with granular cross-platform permissions, comprehensive monitoring, and robust security filtering.

Aegis is the all-in-one platform that helps healthcare providers recover lost revenue by automating insurance denial appeals—from intake to resolution. Built for billing teams, healthcare providers and hospitals.

Adentris is an AI compliance copilot for hospitals and clinics. We are like Grammarly for doctors, finding and fixing mistakes that lead to denied insurance claims or patient lawsuits. The industry today spends $40B doing this manually.

ParaQuery is a fully-managed GPU-accelerated Spark solution providing double the performance at half the cost compared to solutions like Databricks and BigQuery. It is fully Spark-compatible, cloud agnostic, and has seamless integrations everywhere, all without vendor lock-in. ParaQuery makes it trivial to run large SQL and Spark workloads efficiently and serverlessly, without any data migrations.

Rimba integrates fragmented data — PDFs, Excel files, time-series, IoT sensors, equipment telemetry, and system performance data — to complete a workflow, such as populating a database, running analytics, and creating a report. Our software streamlines the entire journey from data capture to report creation for the physical world, starting with heavy industries such as renewables, oil & gas, supply chain, and chemicals. Legacy systems don't communicate, and critical operational data remains siloed. Rimba bridges that gap by connecting data from fragmented systems and structures — ERPs, SCADA, SharePoint, email, and more — to automate workflows, classify inputs, transform data, and improve data monitoring.

Rebolt lets everyone in the company build apps, and agents by speaking with AI. Integrated with your company tools, data and authentication. Replacing no-code tools, bloated SaaS and complex spreadsheets, for automating all the boring work.

superglue replaces brittle SQL scripts, cron jobs, and one-off connectors that power enterprise operations with clean, versioned syncs you can actually understand and trust. It rebuilds the logic behind integrations, so migrating systems, adding tools, or scaling processes no longer breaks everything. Companies running on superglue roll out AI projects faster, spend less on maintenance, and future-proof their business for continuous optimization.

Spott is the first AI-native ATS/CRM for recruiting & staffing firms. We built Spott because existing recruitment platforms require extensive manual work, are clunky to use, rely on fragmented add-ons, and are not designed for AI adoption. Spott combines everything recruiting firms need, from a full ATS & CRM to AI agents across the entire workflow, into one AI-native solution. It enables recruiters to focus on what matters most and close more placements.

Helping manufacturers and distributors automate the process of moving RFQs, invoices, and POs from their inboxes to their ERPs.

Keye is an AI software that lets private equity firms do due diligence for acquisitions faster and more accurately. Our customers can evaluate 10x more deals and fund better companies which leads directly to better returns/more alpha. -- Our system is the first of its kind to instantly generate complex, comprehensive data packs from raw data in any format, directly from the data room. This enables investors to gain an 80% understanding of a potential deal within moments, empowering them to say No to a deal earlier in the process and focus on high-potential opportunities. Traditionally, creating these detailed data packs—like cohort or retention analyses and customer roll-forwards—takes weeks, during which critical details may be overlooked, potentially costing funds millions in missed insights and poor decisions. -- Keye combines cutting-edge AI with deep private equity expertise to deliver powerful, multi-layered insights that go far beyond the simple summarizers and search functions offered by other tools. Our platform dives deep into both quantitative and qualitative due diligence data, offering high-impact analytics crafted specifically for private equity workflows. This isn’t just automation—it’s a purpose-built solution that uncovers actionable insights, fueling smarter decisions and driving true alpha.

At Tiny, we’re building a new kind of ERP system for factories where AI agents automate repetitive workflows. Made for the four million factories still primarily relying on Excel. LLMs now unlock their troves of siloed unstructured data. We see a massive opportunity to build a compound startup and, beyond that, tap into network effects to unlock just-in-time manufacturing across entire supply chains.

Raycaster is an AI document workspace - think Cursor for regulated content, starting with life sciences teams to draft, edit, and review submissions much faster.

Struct cross-references logs, metrics, traces, and your codebase to accurately root-cause eng alerts and bugs. Integrate your entire stack in minutes, auto-investigate every issue, dive deeper at will, and hand-off context to fix in one click.

MagiCode is an AI-powered frontend agent that writes, reviews, and rigorously tests code before pushing a PR—helping busy frontend teams offload complex, repetitive tasks from their workload.

Redouble AI is the solution to scale human-in-the-loop for AI workflows in regulated industries. Instead of having to rely on slow and expensive human reviewers, Redouble’s clients save 80% of staff costs and significantly improve the accuracy and quality of their outputs by integrating our tool into their workflows. Addressing an $11BN market, the company is already generating revenue with its first set of clients. The founders are two serial entrepreneurs (who have built successful companies in AI and health-tech respectively) and a data engineering veteran who has written more than 120 enterprise-grade software applications.

Refactor works closely with large organizations across healthcare, retail, and logistics to safely tackle their most ambitious AI use-cases in record time. We focus on building autonomous systems that call, click, and navigate legacy software systems. We have worked with companies serving tens of millions of customers and with $50B+ annual revenue.

At Dataleap we have one single focus - make knowledge work at your computer fun! Give all the other roles in sales, ops, hr the same super powers that engineers get with Cursor and Claude Code. Dataleap is the first vibe working and vibe automating platform. We enable business teams to automate they work without any help from engineering. No visual workflow builder, no hour long setup or steep learning curve in n8n. Build your AI coworkers in minutes with a fully agent first interface.

Merlin is an AI-powered ERP for construction companies. We provide construction companies with a single, AI-powered platform to manage their entire business operations. Our platform unifies project management, materials management, finance, estimating, and CRM—traditionally scattered across multiple systems—into one cohesive solution. For the first time, construction firms can automate and oversee every aspect of their projects in a single, intuitive system. Today, construction companies pay for 8-17 different tools - that we eliminate the need for. We reduce - Manual work by 60% - Cut software costs by $10,000 monthly - Complete projects 3x faster. Why Now? We're witnessing a perfect storm of factors: decades of stagnation in traditional ERP systems, a multi-billion-dollar industry built on misaligned incentives, and the transformative potential of AI. This confluence creates a rare cyclical opportunity for market upheaval. The last major shift in this space occurred in the 1990s with the advent of digital systems, and now, 30 years later, we're on the cusp of another seismic change. Customers are crying out for innovation and as AI reshapes the landscape, early customer signals indicate an eagerness for smarter, more efficient systems. It's a unique window of opportunity that opens perhaps once in a multi-decade chance to redefine an entire industry's operational backbone. Team: KS, a BITS Pilani grad and successful startup co-founder, and Ayantika, an IIT alumni and tech expert, bring extensive coding and product development expertise together bringing about over a decade of technical expertise. Sneha ( that’s me), with over a decade of experience in supply chain management and lean manufacturing within the construction industry, has lived the pain of using ERPs in this industry.

The Forecasting Company builds planning systems based on our in-house foundation models for time series.

Formula Insight offers Institutional Investors previously inaccessible data. We provide a central repository of financial models so investors can track changes to forecasts, quantify projection accuracy and expedite analysis. This further systematizes the investment process and enables better investment decisions.

Quetzal is the first fully LLM-powered translation and internationalization suite, enabling companies to translate and internationalize their software and content instantly with minimal setup. We also handle all of your internationalization issues, from managing all of your stakeholders to bringing your product and marketing to market. No more waiting days or even weeks for translated content! Deliver a perfect experience to your users in any language, instantly.

Mica's AI agents replace the data ops teams fixing bad data. When bad or missing data breaks the pipeline, and orchestration, retries, and monitoring fail, painful manual review work kicks in, pulling humans in to investigate and patch data issues across systems. Mica does what those humans do: gathering the right information from internal docs and external systems, reasoning across context, and resolving errors autonomously to get the pipeline moving again. The result: dramatically reduce time, cost, and operational drag as your data pipelines scale without scaling ops headcount. Mica turns judgment-heavy data fixes from a manual bottleneck into an automated background process with full auditability.

Superunit deploys AI voice and email agents to complete employment verifications for background check companies—faster, cheaper, and more compliant than internal teams or outsourced call centers. Our agents call and email employers, collect verification data, and log every interaction for audit and compliance. Customers are replacing manual workflows with Superunit to scale without adding headcount or compromising quality. We work with background screeners and banks to process thousands of verifications per month.

Conveo powers your qualitative research from start to finish, all in one platform. Your AI co-worker designs expert research studies, interviews real people and instantly analyzes your videos. Get robust, actionable insights of consumers, users and audiences at scale. Tell powerful stories to your stakeholders within days.

Entangl uses AI to detect and automatically resolve issues in data center engineering and operations, ensuring efficiency and uptime.

CommodityAI builds intelligent automation agents for some of the most operationally complex businesses in the world: physical commodity traders. In trading operations, critical data is often buried in spreadsheets, emails, PDFs, and legacy systems — making workflows slow, error-prone, and overly manual. CommodityAI acts as a digital operator, continuously reading, interpreting, and updating information across the trade lifecycle to keep records accurate and systems in sync. Our agents extract and validate key details from trade confirmations, contracts, vessel updates, and more — turning scattered, unstructured data into clean, structured records that flow directly into CTRMs, ERPs, and other core platforms. No manual entry required. By automating what others still do by hand, we help trading teams move faster, reduce risk, and focus on the decisions that matter most.