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SiPhox Health

Wearable and At-Home protein monitoring with silicon photonic chips

We are developing a new paradigm for consumer health tech wearables by replacing a 100lb optical instrument with an area of silicon smaller than a postage stamp.
Active Founders
Michael Dubrovsky
Michael Dubrovsky
Founder
Diedrik Vermeulen
Diedrik Vermeulen
Founder
Jobs at SiPhox Health
SiPhox Health
Founded:2020
Batch:Summer 2020
Team Size:30
Status:
Active
Location:Burlington, MA
Primary Partner:Jared Friedman
Company Launches
Sai: Cursor for Lab Test Results
See original launch post

TLDR:

  1. SiPhox, already the best option for home blood testing, is launching Sai, an AI lab test analyzer that lives directly in the SiPhox dashboard, just like the Cursor chat lives inside the IDE.
  2. You can use it with your SiPhox results or upload your own PDFs/screenshots of lab tests, they will be automatically parsed and added to the dashboard for discussion with Sai.
  3. Link here to try for free: https://siphoxhealth.com/try-sai

“AI will cure all diseases in the next 10 years.” – Demis Hassabis, CEO of DeepMind (CBS 60 Minutes)

Big claim. Maybe too big.

Something more practical: AI + friction-free diagnostics can wipe out a significant portion of preventable disease if we give people the right tools.

That’s exactly what we’re shipping an early version of today.


What’s new

1. Cursor-style Copilot for Your Labs (Beta)

Upload any lab report—PDF, photo, whatever—and Sai, our GPT-powered assistant, appears as a cursor-style sidebar in your dashboard.

Ask it anything:

  • “Why is my ApoB high if my LDL looks fine?”
  • “Show me habits that would drop my Trig/HDL under 2.”
  • “Review my last several years of test data to see if I might be developing perimenopause.”
  • “Generate a doctor-ready summary of my results.”

Or highlight any section in your dashboard and click Ask Sai

https://youtu.be/B7PZ3QvIEuI

2. Zero-friction At-Home Blood Testing

  • Upper-arm collector (comfortable, collects the sample painlessly in a few minutes)

  • Industry-leading, up to 50 biomarkers in a single kit

  • Overnight return shipping to lab for fast results.

3. Integrated Expert Review

Every report is reviewed by health experts. Insights come from a proprietary database developed by SiPhox experts and clinical advisors based on years of longitudinal testing by thousands of users. You still get human nuance + the flexibility of discussing your results with Sai.

4. Free Biological-Age & Heart-Age Scores

Because a comprehensive dashboard is nice, but north-star metrics make it easier to take action and track progress. We built these scores using proprietary models based on public datasets and years of SiPhox user data.

5. Open Uploads

Not ready to buy a kit? Start by dumping old Quest/Labcorp PDFs into the dashboard for free. We’ve had this feature available for a few months now, and uploads are growing exponentially.


One More Thing 🫀

Heart & Metabolic Program (launched quietly six months ago, now public)

  • Most complete at-home panel for cardiometabolic risk (advanced lipids + insulin resistance markers).
  • Phenotype scoring that fuses glucose-metabolism and lipid data
  • American Heart Association risk score and SiPhox Heart-Age score so you (and your doctor) can see your heart health status at a glance.
  • Access to titrated lipid-lowering medications when needed via telemedicine
  • Full Sai access, of course.

Why We’re Doing This

  • Doctors are time-constrained. They glance at your test results and say “looks normal” even though “normal” ranges are based on lack of active disease, not disease prevention
  • Patients are guessing. Reddit threads and WebMD are too generic
  • AI is finally good enough to translate raw biomarker data into clear, day-to-day actions.
  • Existing doctor-AI tools are focused on symptom analysis and diagnosis, not on labs and long-term disease prevention
  • 60% of Americans have a chronic disease. We want to help these people manage or even reverse their conditions and help the other 40% stay healthy long into old age.

“There’s a new AI agent/chatbot launching every day. Why does the world need another one?”

  1. It’s 100% true that anyone can upload their lab results to ChatGPT or another LLM interface and have a passable conversation about them. Based on our real-world experience with the SiPhox user-base, having a single health dashboard where all of your health data lives makes all the difference. It’s the same reason Cursor is more useful for coding than ChatGPT… the assistant in the IDE and has all the necessary context to collaborate with the user. This is something we wanted to experiment with (and we are looking to get as much feedback as possible on the UI).
  2. ChatGPT and other chatbots do great on generic medical exams but just like a typical primary care physician, they are less trained to handle health optimization and advanced bloodwork. Selecting “deep research” gives better results, but the output still requires an expert to confirm.
  3. SiPhox customized Sai using years of experience repeatedly testing, and coaching tens of thousands of users. This kind of dataset of frequent, comprehensive testing and coaching doesn’t exist publicly (or privately, as far as we know) for LLMs to train on.
  4. We are not an AI company building in a vacuum; we are a hardware and clinical product company building, integrating AI to serve the needs of active users who partner with us every day to improve their health.

Transparently, we are not convinced that this form factor (a chatbot) is the final iteration, but given the state of AI today (latency vs. accuracy and intelligence tradeoffs), this is where we are starting.


TALK TO SAI

  1. Don’t forget to upload past labs → your data and trends are analyzed and displayed in a clear dashboard with the Sai sidebar_: https://siphoxhealth.com/try-sai
  2. Sign up for a home blood test kit subscription → 20 % off for the YC community with code LAUNCHYC20
  3. Are you a business, healthtech startup, clinic, physician or coach? You can utilize all of these features in SiPhox Enterprise, co-branded or white-labeled: https://siphoxhealth.com/partner

Ten years to cure all diseases is optimistic, but giving everyone a personal lab analyst today is how we start making progress.

See you in the dashboard,

The SiPhox Health team

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How is my data handled?

SiPhox does not sell or share your personal data. SiPhox maintains compliance with industry grade security and best data privacy standards.

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The disclaimer:

Sai is an AI-powered assistant (Beta) developed by SiPhox to provide general informational and educational responses based on its training data. Like other AI models (e.g., ChatGPT, Gemini), Sai may occasionally generate incomplete, outdated, or inaccurate information. We are actively working to improve its performance and reliability.

Sai does not provide medical advice, diagnosis, or treatment, and it is not a substitute for professional medical guidance. The use of Sai does not create a doctor-patient relationship. Any health-related content generated by Sai should not be acted upon without first consulting a qualified healthcare provider.

SiPhox disclaims any liability for decisions made based on information provided by Sai. By using Sai, you acknowledge and agree to these limitations and to our Terms of Service and Privacy Policy.

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