Medical Devices Startups funded by Y Combinator (YC) in the San Francisco Bay Area 2024

Forty million men in the US and over 500 million worldwide suffer from urinary obstruction related to benign prostatic hyperplasia (BPH). The majority of men will experience symptoms of this disease at some point in life. BPH, also known as prostate enlargement, leads to urinary straining, frequency, urgency, and sleep disruption. Despite the high prevalence and significant quality of life burden of BPH, established treatments are limited to drugs, which have limited effectiveness, and surgery, which carries a high risk of sexual side effects. The Zenflow Spring is a small implant delivered in the urologist's office in a simple procedure that provides quick and long-lasting symptom relief.

The iSono Health platform combines automated 3D ultrasound technology with cloud computation and artificial intelligence to empower women and their physicians with early detection and monitoring of breast cancer. Our patented compact ultrasound scanner captures 3D images through automatic scanning of whole breast volume in 1 min. The device connects to a smartphone/tablet/laptop and is controlled by our mobile app. The data is transferred to a secure cloud for image processing and storage. Our machine learning algorithm uses acoustic biomarkers to identify abnormal masses. Our platform’s automated operation and software expands ultrasound use in point-of-care diagnostics as well as monitoring of breast health at home, walk-in and mobile clinics. iSono Health offers women and healthcare providers : Safety: No Radiation Actionable Feedback with AI Fast: 2min Scan Easy to Use

Archform is teeth aligner software startup that lets orthodontists create, design and 3D print aligners within their own offices. The idea is to provide orthodontists with a way to better compete against some direct-to-consumer teeth aligner startups and cut down on the cost of Invisalign.

If we've learned anything in the last few years it's that spending time with our friends and family is essential to our well-being and happiness. Unfortunately, loud and noisy places like weddings and family gatherings hinder human connection, especially for the hearing impaired. In fact, the biggest unmet need in the entire hearing healthcare industry is hearing in noisy places. AudioFocus helps patients hear in these environments by only enhancing voices nearby the patients and ignoring ones farther away. We do this using acoustics informed machine learning and custom microphone array design. Our goal is to increase the adoption rate of 37M US adults with hearing loss, only 8M use hearing aids today. Founded by Auditory Neuroscientist & AI expert and a Hearing Aid hardware design expert.

Quadrant Eye is on a mission to improve eyecare access and fight preventable blindness. We're building the next generation eye exam... inside the average American home. Our team wants to enable patients' best and most visually rich lives. To this end, we're looking for curious and nimble minds to help us develop the world's first fully online eye exam and ultimately deliver high-quality eyecare at scale. Some QE highlights: 🐝 We're a team of surgeons, scientists, venture partners, and hackers who mean business. 💸 Our backers include Y Combinator, Khosla Ventures, and the creator of Google Image Search. 🍥 We're a mission-driven company tackling an eye health market worth $USD137B. 🌟 Our core focus is currently the development of patentable deep tech, and our overall vision is to change eyecare for good.

Auricle is a medical device company building a breakthrough neurostimulation implant to restore hearing in millions of patients who no longer benefit from hearing aids, get less than 60% on a word recognition test, but aren't prepared to make the jump to a cochlear implant. Our approach preserves remaining natural hearing through a reversible and less invasive surgery, addressing the key concerns that hold most patients back from getting a cochlear implant (currently the only treatment option for these patients). The company spun out of Stanford Biodesign having completed two acute human clinical studies demonstrating the approach will work. The team is now focused on developing their full implant system for their first clinical trial. Auricle addresses a currently unserved profile of hearing loss that affects a growing population of 3.5 million patients in the US and represents an immediately accessible $1.2B market opportunity with existing reimbursement.

Building a standard-of-care medical device to freeze abnormal cells before they become cervical cancer, in any clinic, anywhere in the world, at 1/10 the cost. -- Ananya Health is building a portable cryoablation unit designed for every primary care clinic in the world. Our beachhead application is cervical cancer prevention -- even though cervical cancer is easy to screen for, 80% of clinics worldwide lack the infrastructure and specialized staff to treat at the earliest stages. Our platform technology allows nurses and lower level health workers to treat at the point of care for 1/10 the cost of traditional ablation, and is the only cryo device that will help us achieve the WHO target to eliminate cervical cancer in our lifetime.

Zeit Medical leverages the power of AI and wearable sensors to deliver peace of mind for those affected by stroke. Zeit’s smart headband immediately detects the onset of stroke and notifies 911. Each year more than 90% of the one million strokes in the US go untreated, resulting in life-long disability and exploding medical costs north of $100b. The lack of timely treatment is the result of delays in alerting the emergency services. More than 10 million Americans with an elevated stroke risk live with constant fear that a stroke may go unnoticed for hours, while they are asleep or alone. The company was founded by Orestis Vardoulis PhD a biomedical & mechanical engineer and expert in digital health (EPFL/Stanford) and Urs Naber MD a critical care physician (Dartmouth/Stanford). They have both seen the devastating effects of stroke in their families and came up with the idea of addressing this unmet clinical need during their Stanford Biodesign Innovation Fellowship.

38 million people suffer from heart rhythm disorders and are recommended to start medications that can save their lives, but require rigorous ECG monitoring to start and remain on these pills. SafeBeat Rx moves beyond diagnostics to guide these therapeutics, powered by our ML ECG software that integrates with existing FDA-cleared wearables to allow seamless physician approval of drug dosing, all from a mobile phone. We are a team of physicians, engineers, data scientists, and machine learning experts dedicated to using engineering to improve heart health.

Acquired by Penumbra (NYSE:PEN).

Mable is a personalized migraine clinic using DNA to find and provide the right medication alongside continuous expert care Using our approach, patients have an 80% higher treatment satisfaction rate, have one extra day per week to enjoy their life and get 55% pain reduction.