Infrastructure Startups funded by Y Combinator (YC) in the San Francisco Bay Area 2026

June 2026

Browse 163 of the top Infrastructure startups funded by Y Combinator. Headquartered in the San Francisco Bay Area, these are some of the hottest and fastest-growing startups. This doesn't include all companies originally founded in San Francisco Bay Area or by founders from there.

We also have a Startup Directory where you can search through over 5,000 companies.

  • Fivetran
    Fivetran
    Y Combinator LogoW2013
    Active • 1,200 employees • Oakland, CA, USA
    Fivetran automates data movement out of, into and across cloud data platforms. We automate the most time-consuming parts of the ELT process from extracts to schema drift handling to transformations, so data engineers can focus on higher-impact projects with total pipeline peace of mind. With 99.9% uptime and self-healing pipelines, Fivetran enables hundreds of leading brands across the globe, including Autodesk, Conagra Brands, JetBlue, Lionsgate, Morgan Stanley, and Ziff Davis, to accelerate data-driven decisions and drive business growth. Fivetran is headquartered in Oakland, California, with offices around the world. 
    data-engineering
    saas
    analytics
    b2b
  • Miso Labs
    Miso Labs
    Y Combinator LogoP2026
    Active • 2 employees • San Francisco, CA, USA
    Miso Labs is building the world’s most emotive foundation models for voice. We believe that the next generation of AI interactions shouldn't just be functional—they should be human. By bringing warmth and lightning-fast speed to the voice layer, we empower developers to build voice agents that users truly love.
    ai
  • Limrun
    Limrun
    Y Combinator LogoP2026
    Active • 1 employees • San Francisco, CA, USA
    Coding agents in the cloud don't work for majority of teams who require native capabilities; they lack XCode for iOS, Emulator for Android, Unity for game development teams. We are on a mission to cloudify every local development utility so that regardless of where it runs, your agent can compose an ideal set of capabilities on the fly so you don't need to run it on your laptop. Today, we provide remote services such as XCode, iOS & Android simulators to enable coding agents running in any sandbox to be able to build and iterate over mobile apps, too. Replit, Rork, Momentic, Minitap and more agent companies have built mobile development and testing experiences on Limrun platform. Coconote (Quizlet), SorceJobs (W25) and more companies with mobile apps use Limrun with their cloud agents, merging PRs without having to check out the code locally.
    cloud-computing
    b2b
    enterprise-software
    artificial-intelligence
  • Wato
    Wato
    Y Combinator LogoP2026
    Active • 2 employees • San Francisco, CA, USA
    Wato gives AI agents shared memory, reusable workflows, connected tools, and living artifacts so work compounds across a team instead of disappearing into chat threads. Teams use Wato to give every agent access to trusted company context and turn useful runs into knowledge the next agent can build on.
    enterprise-software
    ai
  • Expanse
    Expanse
    Y Combinator LogoP2026
    Active • 4 employees • San Francisco, CA, USA
    Expanse unlocks wasted GPU capacity. We recover idle compute through three capabilities: resource prediction (right-sizing job submissions before they reach the scheduler), optimisation suggestions (code and config changes researchers can apply themselves), and failure prediction (catching jobs that will fail before they consume hours of GPU time). We’re four engineers. We ran HPC and GPU training workloads at the largest quant funds and national supercomputing centres. We faced this problem first hand and the only fix was to over-provision and burn millions. Ismaeel built the first multimodal HPC resource predictor as research at EPCC (Edinburgh’s Parallel Computing Centre), which beat every published baseline. This is the tool we wish we had.
    infrastructure
    aiops
    developer-tools
    enterprise-software
  • Zibra Labs
    Zibra Labs
    Y Combinator LogoP2026
    Active • 2 employees • San Francisco, CA, USA
    We build distributed compute clusters with the cheapest CPUs and GPUs across Hyperscalers and Neoclouds for AI. Our mission is to bring frontier-grade infrastructure to everyone. We're starting by building large scale high performance computing (HPC) clusters for quantitative trading firms to run parallel simulation workloads such as backtesting. Our technology generalizes to critical AI workloads such as post-training with reinforcement learning, fine-tuning, long-horizon agents with high tool use, and batch inference.
    cloud-computing
    infrastructure
    fintech
    ai
  • Drip
    Drip
    Y Combinator LogoP2026
    Active • 2 employees • San Francisco, CA, USA
    dripos sends first messages, handles replies, follows up, and books calls across iMessage, LinkedIn, Gmail, Slack, and group chats. You choose who it can message and when it can act.
    messaging
    recruiting
    b2b
    sales-enablement
  • Archal
    Archal
    Y Combinator LogoS2026
    Active • 2 employees • San Francisco, CA, USA
    Archal lets you test agents and code that touch third-party APIs without hitting the real services. We build working clones of popular SaaS platforms that hold state across requests and behave like the originals, so you catch bugs before your agent does something irreversible in production.
    ai
    developer-tools
    infrastructure
    api
  • smol machines
    smol machines
    Y Combinator LogoP2026
    Active • 1 employees • San Francisco
    Smol machines solve the problem of "but app works on my machine" by shipping the machine. Smol machine enables devs to ship a lightweight virtual machine with any software, similar to how Electron ships an entire browser with the web app.
    cloud-computing
    infrastructure
  • StableBrowse
    StableBrowse
    Y Combinator LogoP2026
    Active • 4 employees • San Francisco, CA, USA
    We are making the browser layer for your AI agents. Agents don’t need to see UIs like us humans do. We give agents a semantic understanding of the web instead of brittle visual interfaces. Your agents can perform deep research, large-scale scraping, and complex automation—more efficiently with our knowledge graphs that turns the web into a native protocol for LLMs.
    ai
    api
    automation
    web-development
  • Interfaze
    Interfaze
    Y Combinator LogoP2026
    Active • 5 employees • San Francisco, CA, USA
    Interfaze is an AI model built on a new architecture that merges specialized DNN/CNN models with LLMs for developer tasks that require deterministic output and high consistency like OCR, Object detection, classification, Speech-to-text (STT) and more. Interfaze has outperforms large labs across 9 frontier benchmarks like OCRBench V2, RedCOCO and more. Full benchmarks: https://interfaze.ai/leaderboards Read paper: https://arxiv.org/abs/2602.04101
    deep-learning
    developer-tools
    generative-ai
  • Sazabi
    Sazabi
    Y Combinator LogoP2026
    Active • 10 employees • San Francisco, CA, USA
    The AI-native observability platform for fast-moving engineering teams. Backed by tastemakers from the world's top AI companies: Vercel, Graphite, Daytona, Browserbase, LangChain, Mastra, Replit, and more.
    developer-tools
  • ProjectX
    ProjectX
    Y Combinator LogoP2026
    Active • 6 employees • San Francisco
    Every computer ever made forces you to do one thing at a time. One cursor. One keyboard. One Hardware. One app in focus. Fifty years. Nobody questioned it. We did. We started over. We built InfinityOS, a fundamentally new computer OS on the cloud from ground up. Infinity runs every app in its own independent computer -- own GPU, own input, own environment. Windows and Linux in the same session. Humans and agents working side by side. No concurrency ceiling. Cold start in seconds. runs on the browser of any device..
    infrastructure
    cloud-computing
    devops
    marketplace
    ai
  • primitive
    primitive
    Y Combinator LogoP2026
    Active • 4 employees • San Francisco, CA, USA
    Building the communication infrastructure needed for fully autonomous agents
    developer-tools
    infrastructure
    email
    automation
    ai
  • Minicor
    Minicor
    Y Combinator LogoP2026
    Active • 7 employees • San Francisco
    Minicor connects AI startups to legacy desktop apps that have no API. Reliably, quickly and at scale. Describe a workflow and get an API endpoint. Each call triggers a self-healing desktop automation on a Windows VM. On-prem, cloud, or Citrix. Build through your coding agent via our MCP. Complete with the observability tools to manage your customer relationship: full video replay of every automation, granular logging, and slack enabled alerts.
  • The Token Company
    The Token Company
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    Compression middleware that removes context bloat in milliseconds, lowering costs and improving end-to-end latency. Compression is especially effective across natural language workloads. In a blind LLM arena case study with one of our customers, compressed requests increased user preference, lowered costs, and lifted purchase volume by 5%.
  • IncidentFox
    IncidentFox
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco, CA, USA
    AI SRE agents that automatically learn each customer’s system so they work just like an in-house engineer.
    artificial-intelligence
    developer-tools
    aiops
  • Terminal Use
    Terminal Use
    Y Combinator LogoW2026
    Active • 4 employees • San Francisco
    Terminal Use is an orchestration platform for background agents. Purpose-built for agents that use filesystems. Our platform is CLI-first, making it easy for your coding agents to experiment and continuously improve your deployed agents.
  • Piris Labs
    Piris Labs
    Y Combinator LogoW2026
    Active • 4 employees • San Francisco, CA, USA
    Piris Labs offers a full-stack inference service that eliminates the AI data movement bottleneck. By pairing proprietary photonic hardware with a vertically optimized software stack, we minimize the "memory wall" associated with expensive GPUs. This allows us to deliver the same performance as traditional clusters at a fraction of the cost. Our technology improves effective FLOP utilization and reduces latency, finally making the unit economics of trillion-parameter models sustainable. Founded by a team of MIT physicists and Meta AI experts.
  • Cascade
    Cascade
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    Cascade helps companies take their proprietary data and workflows to align models for their use cases, resulting in higher throughput intelligence that works better, faster, and cheaper.
  • Maven
    Maven
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    We enable AI voice agents to collect payments over the phone through a single API call, handling card processing and PCI compliance across all payment gateways
  • Salus
    Salus
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco, CA, USA
    Your agent processed a refund without looking up the order ID, costing you thousands. You only found out three hours later from a support ticket. Evals, output scoring, and observability can reduce the likelihood of mistakes like these occurring - but there's no solution that inspects and prevents an action as it’s about to execute. Salus does that. We’ve built an API that wraps around your agent and checks its actions at run time, blocking incorrect ones and providing immediate feedback to guide retries. Kevin and Vedant were roommates at Stanford, where they both studied computer science.
    api
    b2b
    infrastructure
    developer-tools
    ai
  • Autumn AI
    Autumn AI
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    Autumn is building the first real-time signal intelligence platform for GTM teams. We monitor posts, commits, blogs, and announcements, surfacing buying signals the moment they appear. Define your ICP and the signals that matter, and we deliver a condensed, real-time feed filtered by intents.
  • Klaus AI
    Klaus AI
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    Get your personal OpenClaw instance on the cloud and connected to your Slack or other messaging app in 3 minutes. Pre-installed security features and common skills.
  • Oximy
    Oximy
    Y Combinator LogoW2026
    Active • 4 employees • San Francisco
    Oximy helps enterprises understand and manage AI usage across their workforce. Used by security, finance, and transformation teams to track adoption, control spend, and manage governance as AI scales.
  • Orthogonal
    Orthogonal
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    APIs weren't built for agents. Orthogonal fixes that. We enable agentic payments so any agent can instantly discover, access, and pay for hundreds of APIs. No subscriptions, no sales calls, just pay per use. API providers list once and get paid every time an agent calls their API.
  • Moda
    Moda
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    Moda is the reliability & monitoring layer for agents. It surfaces patterns across agent hallucinations, laziness, forgetfulness, and tool call failures. While also providing analytics on user frustration, net promoter score, retention, and churn rates. In the next 10 years, with more AI agents spawning and trying to get PMF, developing an agent that actually works for users is critical. Everyone has access to the same models, thus the ones that win on a product level will be the ones who learn fastest from real usage. Moda is that learning layer.
  • Shofo
    Shofo
    Y Combinator LogoW2026
    Active • 4 employees • San Francisco
    We are building the world’s largest video library. We've aggregated billions of videos into a searchable index and use agents to find and label the exact datasets a lab needs on demand. If a lab needs 100K hours of cooking videos where someone is holding a pan, with reasoning annotations on top, our agents search the index, extract the matching subset, route it through our labeling pipeline, and deliver a custom dataset in days, not months.
    data-labeling
    infrastructure
    artificial-intelligence
  • Cumulus Labs
    Cumulus Labs
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    Cumulus Labs lets engineering teams ship AI in production without needing a dedicated ML platform team. Right now, companies building AI products are forced to stitch together separate vendors for routing, observability, evaluation, fine-tuning, and inference. This fragmented approach is brittle, expensive, and is a common reason enterprises fail with AI. We replace that entire stack with a single unified platform. Developers can keep their existing code while instantly upgrading to a unified platform that handles routing, semantic caching, continuous shadow evaluation, simulated data, and one-click fine-tuning. Behind the platform is Ion, our proprietary inference engine running on a custom NVIDIA Grace GPU fleet. Ion uses in-house custom GPU kernels to deliver 30 to 50 percent more throughput than standard vLLM or SGLang, giving our customers SOTA inference economics.
  • RunAnywhere
    RunAnywhere
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    Edge AI is inevitable, but shipping it is painful: every device class behaves differently, runtimes vary, models are huge, and performance collapses under memory/power constraints. RunAnywhere turns that into an enterprise-ready workflow: one SDK to run models on-device, plus a control plane to manage models, enforce policies, and measure outcomes across thousands of devices.
  • Didit
    Didit
    Y Combinator LogoW2026
    Active • 12 employees • San Francisco
    One API for KYC, KYB, AML, biometrics, and fraud — powered by 1,000+ data sources, 200+ signals, and in-house AI models. Global coverage. Integrate in minutes, pay as you go, 500 free checks/month. Start free at business.didit.me.
  • Luel
    Luel
    Y Combinator LogoW2026
    Active • 12 employees • San Francisco
    Luel is a sourcing and licensing platform for rights-cleared multimodal training data at scale. We work with frontier AI teams to provide high-quality bespoke data collections and off-the-shelf datasets.
  • Captain
    Captain
    Y Combinator LogoW2026
    Active • 2 employees • San Francisco
    Captain delivers the most accurate file search engine built for AI agents. We’ll index data from the sources folks already use like S3, SharePoint, and Google Drive, and easily scale multimodal, petabyte-level content search. We’re the Snowflake for Unstructured Data. Captain tops the Open-RAG-Benchmark with over 20% higher accuracy than standard RAG pipelines. We achieve this through robust data processing techniques like embedding normalization across modalities, ensuring that representations cluster by semantic content rather than data type.
    data-engineering
    infrastructure
    b2b
    api
  • Sciloop
    Sciloop
    Y Combinator LogoF2025
    Active • 2 employees • San Francisco, CA, USA
    Sciloop creates expert-level math and physics problems that frontier AI models can't solve, then sells the data to AI labs for training and evaluation. Our problems are created by IPhO and IMO medalists — the top 0.01% of STEM talent globally. On our benchmark, models like GPT 5.4 Pro and Gemini 3.1 Pro score 0-5% on our hardest problems. We work with AI labs to supply continuous, fresh training data that pushes the frontier of mathematical and scientific reasoning. Founded by Bilal and Osman, International Physics Olympiad medalists from MIT with hands-on ML research experience at MIT CSAIL.
    artificial-intelligence
    big-data
    data-labeling
    marketplace
  • Hyperspell
    Hyperspell
    Y Combinator LogoF2025
    Active • 6 employees • San Francisco, CA, USA
    Hyperspell is the Memory & Context Layer for AI Agents. AI agents are clueless geniuses. They crush humans on any standardized test, but wouldn't last a day at a real job. What today's super-intelligent agents are missing is the real world context they are operating in. A context that humans stitch together from hundreds of data points across dozens of interactions and channels. A context that grows with their tasks. Hyperspell gives AI agents this context by connecting to their user’s workspace data and building a personalized memory and context layer.
    artificial-intelligence
    machine-learning
    saas
    data-engineering
  • s2.dev
    s2.dev
    Y Combinator LogoF2025
    Active • 5 employees • San Francisco, CA, USA
    S2 is an API for durable streams. We make working with streaming data dead simple and reliable. The more we worked on data systems, the more we felt like there was a missing building block. The seamless experience of object storage simply did not exist for durable streams – so we set out to fix that! S2 reimagines streams as an unlimited and access-controlled web resource. Like if Kafka and S3 had a baby. - Building agents? Use granular streams to persist context in real time, make workflows auditable, and coordinate between agents. - Publishing fast-moving data? Streams support high fanout and can be accessed directly over the internet, so they are a great fit for broadcasting real-time feeds. - Sandboxing? Emit to per-instance streams, and read history or live events just as easily. - Local-first and multiplayer experiences? Propagate updates reliably and efficiently. Stop dealing with clusters, and start streaming.
    databases
    developer-tools
    api
    infrastructure
  • Dedalus Labs
    Dedalus Labs
    Y Combinator LogoS2025
    Active • 10 employees • San Francisco, CA, USA
    The fastest persistent computer for agents. Host long-running, stateful agents that never sleep in <250ms.
    artificial-intelligence
    developer-tools
    devops
    workflow-automation
  • Imprezia
    Imprezia
    Y Combinator LogoS2025
    Active • 3 employees • San Francisco
    The first advertising infrastructure designed specifically for AI apps. Seamlessly integrate contextual brands & products that enhance user experience while generating revenue to pay the inference bills.
  • truthsystems
    truthsystems
    Y Combinator LogoS2025
    Active • 6 employees • San Francisco, CA, USA
    Truth Systems provides a compliance agent to govern the use of generative AI. It translates operational policies into intelligent, real-time guardrails that monitor every AI interaction. This empowers companies to proactively block non-compliant actions and align access to AI tools with user competency. By eliminating the risks and operational blind spots associated with uncontrolled AI adoption, our platform enables enterprises to fully leverage the technology's potential without compromising security. We are establishing the new standard for AI governance, building a future where every professional can innovate safely and confidently.
    b2b
    artificial-intelligence
  • KERNEL
    KERNEL
    Y Combinator LogoS2025
    Active • 6 employees • San Francisco, CA, USA
    Kernel is crazy fast, open source infra for AI agents to access the internet 🧠🕸️ - Built on unikernels for crazy fast cold starts and low resource usage - Sub-150ms cold starts on managed headful browsers - Built-in stealth mode with residential proxies and automatic CAPTCHA solving - Full observability: session recording, live view, and full logs - Persistent sessions that maintain cookies and auth across invocations - Native support for all browser and computer use frameworks - SOC 2 compliant and HIPAA-ready Trusted by Cash App, Rye, and 1000+ others. Backed by Accel & Y Combinator (S25).
    developer-tools
    cloud-computing
    infrastructure
    ai
  • Manufact (formerly mcp-use)
    Manufact (formerly mcp-use)
    Y Combinator LogoS2025
    Active • 5 employees • San Francisco
    Manufact provides open-source dev tools and infrastructure for MCP to help dev teams quickly build and deploy MCP Servers for AI agents & MCP Apps for ChatGPT and Claude. We developed the mcp-use SDK, which has over 7M downloads and 10,000 GitHub stars, and is used by 20% of the US 500. Create MCP servers/apps in minutes, connect your GitHub repo, and make them immediately available to AI agents and ChatGPT.
    ai
    open-source
    developer-tools
    infrastructure
    b2b
  • Pangolin
    Pangolin
    Y Combinator LogoS2025
    Active • 3 employees • San Francisco, CA, USA
    Pangolin is an open-source, identity-based remote access platform built on WireGuard that enables secure, seamless connectivity to private and public resources.
    networks
    open-source
    enterprise-software
  • Modelence
    Modelence
    Y Combinator LogoS2025
    Active • 3 employees • San Francisco, CA, USA
    You built the demo in a weekend. Now you need auth, a prod-grade database, real-time events, AI observability, cron jobs, email, monitoring… and you needed them yesterday. We spent a decade at our previous startup, building a platform while scaling to millions of users and customers like Meta & Netflix. Now we put that into an open-source framework, so others wouldn’t have to do the same from scratch. Modelence is a batteries-included production ready platform for agentic development that abstracts away boilerplate so you can just focus on building your product logic and deploy it to production without worrying about infrastructure. Shipping production apps is much harder than building a prototype that runs locally and 95% of all production apps share the same building blocks. We did a massive amount of work on our previous platforms that was not specific to our product, and we’ve created Modelence to abstract that away: - Authentication - Database setup - Hosting / CDN - AI integration (LLM observability, prompts) - Real-time events - Cron jobs - Email service - Monitoring - Analytics - Admin dashboards Andrej Karpathy recently posted about this same exact problem: https://x.com/karpathy/status/1905051558783418370 and explained it further in his YC AI Startup School talk: https://youtu.be/LCEmiRjPEtQ?feature=shared&t=1940
    developer-tools
    infrastructure
  • Luminal
    Luminal
    Y Combinator LogoS2025
    Active • 5 employees • San Francisco
    Luminal builds an ML framework and compiler that generates GPU code. Our stack 10x's model speed while simplifying deployment and cutting idle GPU costs Github: https://github.com/luminal-ai/luminal Discord: https://discord.gg/APjuwHAbGy
    artificial-intelligence
    aiops
    cloud-computing
    developer-tools
  • AgentMail
    AgentMail
    Y Combinator LogoS2025
    Active • 8 employees • San Francisco, CA, USA
    AgentMail is the email inbox API for AI agents. It gives agents their own email inboxes, like Gmail does for humans.
    developer-tools
    api
    email
  • Kairos
    Kairos
    Y Combinator LogoP2025
    Active • 2 employees • San Francisco, CA, USA
    Kairos closes the last-mile reliability gap in AI deployments. We bring frontier techniques to companies in critical industries, deploying specialized agents that encode operator expertise and reliably automate their most manual workflows.
    reinforcement-learning
    aiops
    machine-learning
    ai
  • Sixtyfour
    Sixtyfour
    Y Combinator LogoP2025
    Active • 8 employees • San Francisco, CA, USA
    Sixtyfour deploys AI agents that investigate people and companies across the open and dark web, official records, proprietary databases, and unstructured sources. We resolve identities, map entity relationships, and surface risk signals for teams where data quality is essential.
    artificial-intelligence
    infrastructure
    b2b
    enterprise-software
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