Healthcare Startups funded by Y Combinator (YC) in the San Francisco Bay Area 2024

Notable Labs is building a personalized drug discovery platform to identify treatment options for relapsed and refractory cancer patients — starting with blood cancer — to address the long tail of cancer treatment. We look at a person’s actual cancer cells, test combinations of FDA approved drugs, and see which combinations kill the cancer cells and leave the healthy cells alive. We focus on combinations because cancer is often difficult to target with just one drug and starting with a single drug can lead to resistant clones or relapse. We're building a highly automated lab in Foster City running on our custom software and are currently testing relapsed/refractory cancer patients as well as samples from a variety of pharma/biotech partnerships. https://www.notablelabs.com/careers

Diassess Inc. is revolutionizing the way infectious diseases are prevented, diagnosed, and monitored by developing the tools necessary to empower people to become knowledgeable about their health. We produce inexpensive, disposable health diagnostic hardware that transforms any smartphone into a portable, real-time health-monitoring device for rapid, accessible, multiplexed analysis of bodily fluids anywhere in the world.

We make oral drugs to treat and prevent viral infections - like COVID-19.

The Human Diagnosis Project (also referred to as “Human Dx” or “the Project”) is a worldwide effort to build an open medical intelligence system that maps the steps to help any patient. By combining collective intelligence with machine learning, Human Dx intends to enable more accurate, affordable, and accessible care for all

At AgileMD, we are building the most advanced real-time predictive analytics and clinical algorithms platform for hospitals. Our cloud-based engine helps thousands of doctors and nurses around the country make medical decisions, so that every patient receives the highest quality and value of care based on the latest medical knowledge and data.

Medmonk is a technology platform that helps fight non-adherence. It enables pharmacists to provide financial assistance to patients who are unable to pay for their medications. We partner with pharmaceutical companies, pharmacies, physicians, and health plans to improve outcomes by promoting access to chronic therapy. Medmonk is based on the premise that it's in everyone's best interest for medications to be used regardless of price. Patients get the care they need, insurers are protected against larger claims, and pharmaceutical companies and pharmacies get maximum use of their medications.

Have you ever wondered why it's so hard for physicians to communicate quickly and why the leading cause of preventable death is still a delay in communication? Our team has built the solution for this. Medigram is a team of tier 1 health system CxO IT executives, technologists, SaaS exec, physicians, engineers, and data experts. We have developed a breakthrough service for the medical industry to save lives and for hospitals to make millions per year. Medigram instantly flags insights from clinician chats for immediate insight into hospital operations and patient care. This reduces critical response times by 50%. We've designed this system to provide instant, reliable messaging (including images and audio files) across very complicated network environments in hospitals. Medigram is secure, designed for HIPAA, and a full stack system which includes database back end, middleware, logic, and client apps for iOS, Android, desktop, and the web. Our solution to this is Mobile Intelligence For Healthcare by providing a secure, intelligent workflow management platform for the patient care ecosystem and medical professionals. Within the healthcare environment, you have physicians, the patient care team, EMR, workflow, data, and administration which needs to be tied together with intelligence through Medigram.

Healthcare needs good data. At PicnicHealth, we are building deep real-world datasets fueling cutting-edge research while giving patients control of their own medical record data. These complete, clinically-rich datasets produce unique insights — across dozens of diseases — to ultimately get the right treatments into patients’ hands faster. We work directly with patients and leverage state of the art machine learning to transform messy medical records into structured, research-ready datasets. To date we’ve helped tens of thousands of patients securely access their records and proactively contribute to advancing research in diseases that impacts their lives.

SimplyInsured was founded with one mission: to eliminate fear from health insurance. By changing the way small business owners purchase health insurance with our 100% online platform, we’re transforming a $20 billion dollar industry and delighting thousands of customers. Our unique values-based culture (and extremely talented team) is our core competitive advantage, and each person on our team makes a direct, immediate impact on our business. We value transparency, feedback, bias to action, growth, and an obligation to dissent. Every opinion is respected, we hold each other to extremely high standards, we’re driven by the diversity in our backgrounds, and unified by 100% alignment on our mission. What’s best for the customer is the heart of everything we do, and our customer stories prove it: by changing health insurance we’re literally saving lives. Based in San Francisco, SimplyInsured was founded in 2012 and is back by Bessemer Venture Partners, Polaris Ventures, and Y-Combinator. If you’re up for the challenge of improving health insurance for millions of Americans, we’re just getting started, and we’re growing!

The world’s No. 1 lab management platform. We help scientists easily organize orders, manage inventory, and save money.

Science Exchange powers R&D outsourcing for the world’s top life sciences companies. Our marketplace gives scientists access to the innovation and research they need and our platform fully automates R&D outsourcing from source to pay so scientists can focus on what they love—science.

Qventus’ mission is to simplify how healthcare operates so it just works — for everyone. The company offers an AI-based software platform that helps hospital teams make better operational decisions in real-time. Qventus addresses operational challenges across the hospital including emergency departments, perioperative areas, patient safety, in-patient, outpatient and pharmacy. Located in Silicon Valley, Qventus is honored to be working with leading public, academic and community hospitals across the United States. Founded in 2012, Qventus was named among Fast Company’s Most Innovative Companies for 2018. The company has also been recognized as a leader and innovator in operational excellence, with the 2016 Fierce Innovations Award in Healthcare and Healthcare Informatics 2017 Innovator Award. For more information about Qventus, please visit www.qventus.com

Shasqi is leading the development of therapeutics leveraging click chemistry to get active cancer treatments to tumors with its proprietary CAPAC™ platform. Our technology is based on localizing a click chemistry reagent in the tumor area, which then activates a second agent, a systemically infused protodrug. When the two 'click', a powerful localized therapy is activated at the tumor, while keeping its systemic exposure levels below toxic thresholds.

We’re building technology to finance universal healthcare by crowdfunding surgeries and providing coverage for primary care.

Atomwise is a preclinical tech-enabled biotech using machine learning for hit discovery, hit expansion, and lead optimization. We were the first team to apply convolutional neural networks to drug discovery. We focus on identifying and optimizing novel small molecule scaffolds and unlocking previously-undrugged protein targets.

At iMicrobes, we believe there are opportunities for biology to solve our biggest problems. Our mission is to work with the world’s largest companies to use new raw materials and recycle waste for chemical production, polymers, agriculture, and space exploration.

We are a B2B medical device and data company passionate about providing remote monitoring solutions for the proactive care of chronic disease patients. Our core expertise and IP is in continuous respiratory sensing. Spire Remote Patient Monitoring is used by pulmonologists and patients throughout the United States. To date our sensors have been worn by more than 150,000 people.

We enable people to live their best lives. As we succeed, there is more convenience, healthier communities and thriving businesses. We get medications to those who need them and improve information, access and management of their care and enable businesses to move online and gain access to consumers who need their services

SmartSpot is a post Series-A stealth startup backed by Founders Fund and Khosla Ventures that uses computer vision to deliver an unparalleled fitness training experience to your home. Our unique hardware solution gives amazing trainers the ability to see their class participants in real time and deliver detailed advice that was previously only possible in person.

Forty million men in the US and over 500 million worldwide suffer from urinary obstruction related to benign prostatic hyperplasia (BPH). The majority of men will experience symptoms of this disease at some point in life. BPH, also known as prostate enlargement, leads to urinary straining, frequency, urgency, and sleep disruption. Despite the high prevalence and significant quality of life burden of BPH, established treatments are limited to drugs, which have limited effectiveness, and surgery, which carries a high risk of sexual side effects. The Zenflow Spring is a small implant delivered in the urologist's office in a simple procedure that provides quick and long-lasting symptom relief.

Founded in 2012, Transcriptic has developed the first robotic cloud lab platform for on-demand life science research. It’s powered by the Transcriptic Common Lab Environment (TCLE) a scalable, digital infrastructure that integrates laboratory processes, instruments and IoT technologies into a single user interface. Researchers can carry out scalable, reproducible and rapid experimentation from anywhere in the world. Top ten pharmaceutical companies, as well as emerging biotech companies, are using the platform to gain more reproducibility and flexibility in the design and control of their experiments. By leveraging cloud-based technologies, users can access the power of a fully automated laboratory – whether in their own labs through an on-premise deployment of TCLE or through Transcriptic’s Bioassays services – all through a simple web-based interface. Transcriptic is transforming drug discovery and synthetic biology research by helping scientists focus on accelerating discoveries instead of labor-intensive bench work.

Bodyport’s cardiovascular sensing weight scale and predictive algorithms detect early changes in cardiac function to help prevent avoidable hospitalizations. Bodyport is initially targeting heart failure, a chronic condition affecting over 6M Americans and a leading cause of hospitalizations (1M/year) and healthcare spending ($35B/year). Bodyport’s novel scale measures cardiac output, congestion, heart rate, and other leading indicators of cardiovascular health — all in the same step patients already take to weigh themselves. Companion algorithms and software empower care teams to quickly identify at-risk patients and remotely optimize their therapy to prevent deterioration.

Circle Medical is a venture-backed Y-Combinator healthcare startup on a mission to bring quality, delightful primary care to everyone on the planet. Built by top-tier physicians, engineers, and designers, our medical practice and underlying technology have pioneered how people find and receive care. Our focus on building directly for our patients and providers to address serious care accessibility issues has enabled us to grow over 3X year-over-year. We’re now using our most recent round of funding from WELL Health, backed by Sir Li Ka-shing, to continue building out our hybrid in-clinic and telemedicine model across all fifty states. As we enter the hypergrowth phase, we are looking for deeply motivated team players who are driven to solve some of the biggest challenges in healthcare so that people can live longer and healthier lives. More about us can be found on our website!

Verge uses artificial intelligence and human data to develop better drugs faster. Verge has an end-to-end technology-driven drug discovery and development platform, featuring one of the field’s largest and most comprehensive proprietary patient genomics datasets from human tissue. Verge uses machine learning to mine this data and develops these insights into new drugs using it’s human-centric biology and chemistry platforms.

The iSono Health platform combines automated 3D ultrasound technology with cloud computation and artificial intelligence to empower women and their physicians with early detection and monitoring of breast cancer. Our patented compact ultrasound scanner captures 3D images through automatic scanning of whole breast volume in 1 min. The device connects to a smartphone/tablet/laptop and is controlled by our mobile app. The data is transferred to a secure cloud for image processing and storage. Our machine learning algorithm uses acoustic biomarkers to identify abnormal masses. Our platform’s automated operation and software expands ultrasound use in point-of-care diagnostics as well as monitoring of breast health at home, walk-in and mobile clinics. iSono Health offers women and healthcare providers : Safety: No Radiation Actionable Feedback with AI Fast: 2min Scan Easy to Use

Founded in 2010, Lygos is providing biotechnology solutions for today’s renewable chemical challenges. They engineer microbes to convert sugars into high-value, industrial chemicals, targeting compounds where biological production is cost-advantaged over petrochemical production.

Perlara 1.0 (Feb 2014 - Feb 2019) launched early R&D joint ventures called PerlQuests with highly motivated rare disease families, companies or impact investors. We screened gene-edited patient avatars for repurposable drugs in order to build a predictive R&D engine called ArkBase. We planned to monetize programs based on ArkBase predictions by selectively spinning out asset-centric clinical development NewCos. Perlara 1.5 (March 2019 - April 2020) was the transition to a one-person virtual clinical development company and when the epalrestat and aripiprazole repurposing trials were launched at Mayo Clinic for the treatment of PMM2-CDG and NGLY1-CDDG, respectively. Perlara 2.0 (May 2020 --> The first decentralized and distributed biotech

Qvin is the first and only healthcare service to scientifically prove menstrual blood can test for critical health information – just like a traditional laboratory blood test. Women's health has always been under-prioritized in science. We still operate in a world built by men, for men. It’s why in 2014, Dr. Sara Naseri and Søren Therkelsen started Qvin to research, develop, and patent a product that powers an underserved and understudied population—women. Over 70% of the decisions our doctors make are influenced by blood test results. Every month, 1.8 billion people across the world menstruate. However, the blood our bodies naturally deliver every month has never been explored as a testing source. And yet, menstrual blood has been left unexplored. Qvin is the first and only healthcare service to use period blood as a non-invasive blood test. We exist to give women an easy, insightful way to monitor existing health issues, proactively screen for others, and go into doctor visits more informed and confident of their own health. Our health technology platform helps women manage their health better through a non-invasive blood collection device named the Q-Pad™. All of us at Qvin want to move the study of women forward. We want to close the gender data gap. And we stand for every person who identifies with women, however they define it.

BillionToOne has developed a DNA molecular counter that increases the cell-free DNA diagnostics resolution by over 1,000 fold, which unlocks transformative improvements in prenatal screening and liquid biopsy for cancers. Unity Screen, BillionToOne's commercially available non-invasive prenatal test (NIPT), is the only NIPT that can assess fetal risk for both recessive conditions and aneuploidies from maternal blood. UNITY Screen continues to grow exponentially and is on its path to becoming the next standard-of-care, with an increasing number of publications showing its accuracy and advantages over other screening methods. We have also recently used our molecular counting technology to develop liquid biopsy tests, which have the potential to completely transform oncology care.

Synvivia applies chemical control over cell behavior. This allows us to optimize biomanufacturing of high-value biopharmaceutical products.

At Athelas, we're bringing simple, life-changing health care products to people around the globe. The future of healthcare is at the home - we are a team of technologists building the next generation of medical products at the intersection of hardware and software. We won’t stop until we’ve brought the world class tools of a hospital to your home. Athelas Remote Patient Monitoring (RPM) allows healthcare providers to monitor patient vitals like blood pressure, weight, and blood glucose without the patient ever having to enter a clinic, improving patient health and engagement, and reducing hospitalizations. We do this all through a beautifully integrated suite of devices and software tools that provides access to state-of-the-art technologies and groundbreaking AI powered analysis.

Healthcare is delivered by teams – nurses, doctors, and staff, specific to each hospital, clinic, and department. They want to do their best, but cannot keep up with constantly changing information. Burnout >50%. Unprecedented turnover. Growing medical errors (the #3 cause of death in the US). $100B+ in waste. Elemeno Health is a UCSF and Y Combinator-backed B2B SaaS for healthcare facilities– “a playbook in your pocket,” customized to support frontline teams with bite-sized training and communication at their fingertips, accessible 24/7 on any device. Our efficacy is demonstrated in our published results, passionate clients, and consistent renewals. 20x ROI. 75% decrease in medical errors.

Our mission is to improve quality of life for millions of people by providing easy, immediate access to the world’s best sleep care. Sleep Reset is a digital, personalized sleep clinic, available in a convenient mobile app for iOS and Android. Our program was designed in partnership with leading sleep experts from top sleep clinics and universities. The program improves sleep and reduces sleep anxiety with the most effective methods from sleep clinics, including strategies based on Cognitive Behavioral Therapy for Insomnia (CBT-i) which are proven to be more effective than sleeping pills. Throughout our program, each member is paired with a dedicated sleep coach who personalizes their program. It’s a life-long, sustainable solution to sleep better in weeks, with no pills or melatonin needed – which means no grogginess, side effects, or dependency. Sleep Reset has been covered in Forbes, TechCrunch, and INSIDER. The company was founded by Yunha Kim, a serial entrepreneur recognized by Forbes as 30 Under 30 and is backed by top Silicon Valley investors including YCombinator, Foundation Capital, New Enterprise Associates, Stanford University and 20+ founders/executives of leading companies.

Today 90% of people can't afford to visit a Dermatologist. Our apps automatically analyze the skin or hair using our AI technology and then deliver a customized treatment kit to the customers' doorstep. We have 2 brands: 1. MDacne - the #1 dermatology app in the US & UK App Store. Millions have downloaded MDacne to analyze their acne and get a customized treatment kit. 2. MDhair - the first-ever fully customized hair regrowth treatment kit. Using MDhair, people with hair loss can analyze a picture of their scalp and get a personalized hair regrowth treatment. Our team combines the highest levels of expertise in dermatology, AI, and digital marketing. Come and join us on the mission to build the future of Dermatology!

Intracellular delivery is the most problematic step in T cell immunotherapy discovery, development and manufacturing. Indee Labs is developing a non-viral intracellular delivery system based on microfluidic vortex shedding (µVS) to rapidly deliver nucleic acids, proteins and gene editing complexes to patient and donor T cells with minimal perturbation.

Out-of-pocket healthcare costs are skyrocketing and every day, people all across America are forced to make difficult decisions about their health. Lively is the benefits solutions provider that gets it right. We designed our solutions to take the guesswork out of managing benefits. And our innovative features are built to simplify benefits administration and evolve with your business. Managing wellness and wealth takes more than a series of transactions. By combining robust features with unparalleled service, we make benefits administration effortless, even when time and energy are limited. Experience benefits administration as it should be with Lively. Go to www.livelyme.com to learn about how HSAs other modern employee benefits can help you and your team.

Novel quantitative virtual microscopy for early detection of Alzheimer's disease from non-invasive MRI.

Our API-connected healthcare infrastructure empowers our partners to deliver world-class patient experiences. We power prescribing, lab testing and pharmacy fulfillment.

Carrot is a simple and affordable way for companies of any size to build or enhance their fertility benefit. Carrot can help with egg freezing, infertility treatments including in vitro fertilization (IVF), LGBT+ conception, and more. Fertility care is daunting and scary; our focus is on improving the employee experience during high impact moments related to fertility-- helping save time, money and stress.

Full Sleep by Koko Labs is the first at-home sleep program that combines the power of clinical grade, radar based wireless sleep tracking with best-in-class CBT-I sleep techniques. Full Sleep delivers daily lessons developed with evidence-based principles. The multi-week curriculum is customized based on your daily overnight sleep data and other health conditions that could impact sleep, such as menopause, chronic pain, or depression. Learn how to challenge assumptions, change habits, and introduce behaviors to help you fall and stay asleep.

Vision Disease cause innumerable cases of preventable blindness globally - 415 million diabetic patients worldwide are susceptible to Diabetic Retinopathy (DR), Glaucoma, and more. Current screening protocols for vision disease require ophthalmologists to manually diagnose patients through visual assessment of the fundus. Given the large number of diabetes patients in various communities, this process is expensive, inefficient, and an undue burden on eye clinics.

Rev Genomics is a plant biotechnology company that provides breeders, growers, and retailers with novel cultivars to differentiate themselves in high value markets.

Blueberry Medical provides concierge pediatric care with at-home medical diagnostics and an always-available team of Pediatricians. Blueberry handles twice as may illnesses as any other telemedicine provider and has proven to reduce ER costs by 50%.

Formerly known as Patchd Medical Wearable technology and AI to predict and prevent sepsis outside of hospital.

Nectome is a neuroscience startup that aims to preserve the brain and keep all its memories intact. The company is building the next generation of tools to preserve the connectome. The connectome is all the connections called synapses between neurons in the brain. Researchers from the company is now learning to manipulate individual memories, building advanced brain prosthetics, and reverse-engineering the brain.

Our lead candidate is a multifaceted attack antibody for ovarian cancer. Our approach enables targeting primary cancer cells directly, alongside enabling the immune system's natural anti-cancer function, all with one therapeutic antibody.

Modern Health is the leading mental wellness platform that combines clinically validated assessments, personalized stress management support, an international network of certified behavioral health coaches, and licensed therapists to deliver mental health support across a broad range of individual needs. Modern Health empowers employers to lead the charge in helping their employees be less stressed, more engaged, and happier through evidence-based technology and professional support. Modern Health has raised over $170M from top investors Battery Ventures, Kleiner Perkins, Founders Fund, and John Doerr and supports over 200 companies globally including Lyft, Pixar, SoFi, Credit Karma, Electronic Arts, Cooley, and Okta.

Dear Brightly offers prescription skin products online. Our mission is to get people access to the most effective, dermatologist vetted skincare products for healthy skin, using technology.

Correlia Biosystems is a UC Berkeley spinoff company based in Berkeley, CA. Correlia develops innovative microscale tools that accelerate rapid quantification of biomolecules. Our versatile "SimpleScan" technology opens up new biological questions from one microliter of sample, with rapid results that allow for dynamic monitoring of protein expression profiles (rather than simple end-point measurement). Applications range from enabling next-gen proteomic data sets to point-of-care diagnostics.

Memora Health helps healthcare organizations digitize and automate complex care workflows, making them simple for patients and clinicians to navigate. Memora ingests existing data on clinical workflows, converts them into cohesive messaging journeys that guide patients through their care episodes, and automates the completion of simple follow-up tasks in the EMR. Memora's platform reduces care team notifications by nearly 40%, has a >70 average NPS, and has improved clinical outcomes across various populations. Contact us at info@memorahealth.com

Archform is teeth aligner software startup that lets orthodontists create, design and 3D print aligners within their own offices. The idea is to provide orthodontists with a way to better compete against some direct-to-consumer teeth aligner startups and cut down on the cost of Invisalign.

ZBiotics is a synthetic biology company founded in 2016 and headquartered in San Francisco, California. The company bioengineers probiotic bacteria for nutraceutical and other applications. They launched the world's first genetically engineered probiotic in 2019 – a probiotic that breaks down a toxic byproduct of alcohol. They are currently developing a pipeline of additional engineered probiotics for other consumer health applications.

Culture Biosciences grows cells for biotech companies. Our customers genetically modify organisms to produce new therapeutics, materials, fuels and foods. We help them quickly run experiments and develop manufacturing processes so they can get their products to market faster. We've built proprietary software and automation systems to make operating our bioreactors more efficient than existing systems. We also provide customers with new software tools that help them analyze and contextualize their data. We are currently serving a number of biotech customers and scaling out our infrastructure.

Cancer is a genetic disease. We know this from decades of human and veterinary cancer research. Precision medicine and targeted therapies are successfully used to treat humans with cancer. At FidoCure®, we bring this approach to the world of veterinary medicine. FidoCure® empowers veterinarians to offer genetic sequencing and targeted therapies to treat dogs with cancer. We are committed to expanding the veterinary oncology toolbox for both diagnostics and therapeutics. Our veterinary partners have treated thousands of dogs over the past 30 years and work closely with the growing FidoCure® network of over 143 clinics and 180 forward-thinking veterinary oncologists throughout the US. Together, we can combat canine cancer!

Curebase is reinventing decentralized clinical trials to help the vast majority of potential patients that currently cannot access clinical research. Curebase’s vision is that any patient, no matter where they are located, should be able to participate in clinical trials at home and with their own doctors. This is made possible through a unique suite of tools, including all-in-one eClinical software and virtual research sites, designed to engage patients in clinical trials across all settings, be it at home, at their local clinic, or other places in their community.

Our vision is to provide regenerative medicine treatments that free patients from chronic liver disease and help usher in an era where diseased and damaged tissues can be repaired.

64x Bio is building a platform that radically increases the speed and scale of mammalian cell line discovery. Using a novel high throughput discovery and screening platform and an integrated computational design loop, we are developing new ways of generating highly optimized and otherwise unattainable cell lines for the manufacturing of viral vectors, with a specific focus on those used for cell and gene therapies. Our platform technology enables pharmaceutical and biotechnology companies to bring cell and gene therapies to patients more effectively, providing purpose-built genetically engineered cell lines to increase the efficiency of viral vector production and reduce the cost of manufacturing.

We're a primary care practice that helps residents of senior living communities lead healthier, happy lives. Our mission is to keep senior living residents healthy—by keeping them away from hospitals where exposure to health risks is high. Through our new clinical care delivery model, we bring clinicians right into senior living communities, providing safer, more convenient primary care. Pine Park partners with senior living communities to provide primary care to their residents, building a value-based care model where we keep patients healthier. This allows us to provide comprehensive healthcare on-site, see patients regularly, and better support their holistic health.

We are developing utility-scale molecular sensing using gamified citizen science and a unique, toy-like R&D device.

MentalHappy is a tele-health platform that allows health professionals to facilitate online support groups.The MentalHappy app allows health professionals to facilitate online support groups to help meet the rising demand for mental health services, create meaningful impact and earn extra revenue. Some groups are more intimate, while others have 100+ members, spanning different life events from grief support, healing from illness, life after divorce, black mental health, LGBTQIA+, stress management, emotional fertility support, coping with anxiety, and many other groups.

Delivery of TERT mRNA extends telomeres sufficiently in a few days to reverse over a decade of telomere shortening during normal aging. We are advancing TERT mRNA-based therapies to the clinic.

We quantify brain health and align patients with the right treatment

Probably Genetic is changing the lives of patients living with severe, complex diseases. Our data platform is used by drug developers and patient advocacy groups to develop and launch treatments for these patients. Our technology discovers undiagnosed patients online, analyzes their disease state using machine learning and at-home testing, and enables compliant communication with patients. In doing so, we help patients access diagnoses, clinical trials, and treatments as early as possible.

Bunkerhill is a Sequoia-backed company whose goal is to increase the adoption of AI in healthcare, in order to help doctors catch deadly diseases earlier. Bunkerhill Health has built a consortium of research institutions (Stanford, Johns Hopkins, Harvard, etc.), who develop and validate AI algorithms seamlessly under our legal umbrella (less than one week of setup time for a new project when using the Bunkerhill consortium, versus a year or more for projects outside the consortium). Bunkerhill then manages the FDA clearance and commercial sales process for the algorithms that these institutions develop and validate with us. We’ve signed commercial contracts and deployed algorithms with the world’s leading health systems—UCSF, Mayo Clinic, Georgetown/MedStar, and several others. These algorithms help doctors identify patients earlier than has otherwise been possible, leading to better treatment outcomes (early clinical screening for heart disease, pancreatic cancer, etc.) We’re backed by world class investors: Sequoia, Max Levchin (co-founder of PayPal and Affirm), YC, DCVC, and Pacific8.

Intatct is developing an advanced materials platform to improve the way drugs are delivered and absorbed in the digestive tract. Our vision is to improve the treatment of a wide range of gastrointestinal disorders that are currently underserved.

Endpoint Health is on a mission to address urgent needs in immune-driven critical and chronic illnesses by delivering therapies that are personalized to each patient’s biology. We built Endpoint Health from the ground up to develop and commercialize therapeutics and therapy-guiding tests, to ensure that every patient receives personalized treatment that will dramatically improve their outcomes. Our vision is a world in which all patients have effective, personalized treatment, because therapies are targeted to the right patient at the right time.

YourChoice Therapeutics is revolutionizing the global contraceptive market. Our vision is to develop non-hormonal contraceptives to provide both women and men with birth control options that lack the associated risks of hormone-based options but are equally effective. Traditionally, it has been the women’s financial and health burden to have a contraceptive in place. Our first goal is therefore to bring a novel non-hormonal, on-demand and low cost female contraceptive to the market that will substantially improve their quality of life and well-being. Our second goal is to develop the first ever non-surgical and highly effective non-hormonal contraceptive for men. Currently, male contraception is limited to two main options – vasectomy or condoms. Having such options available to both women and men will globally allow for much better family planning, reduce the number of unwanted pregnancies including abortions and therefore reduce costs and ensure contraceptive health and well-being.

We help healthcare companies run their practices. Eligibility, BI, claims, patient payments? Shoot us an email at founders@aperohealth.com Apero is a Y-Combinator-backed startup based in San Francisco bringing transparency and ease to medical billing. As one of the top startups from the Summer 2019 Y Combinator batch, we have raised from well-known investors including the creator of Gmail Paul Buchheit and the founders of Doctor on Demand, Gusto and Reddit, and serve startups that have raised over $1B in Venture Capital. The founding team are Stanford CS and Berkeley grads and include the CTO of Doctor on Demand having helped raised $240m and process millions of video calls. We are also hiring for engineers and product-minded operations people interested in giving price transparency to patients and providers. We serve practices nationwide, and integrate with leading EHRs as well.

If we've learned anything in the last few years it's that spending time with our friends and family is essential to our well-being and happiness. Unfortunately, loud and noisy places like weddings and family gatherings hinder human connection, especially for the hearing impaired. In fact, the biggest unmet need in the entire hearing healthcare industry is hearing in noisy places. AudioFocus helps patients hear in these environments by only enhancing voices nearby the patients and ignoring ones farther away. We do this using acoustics informed machine learning and custom microphone array design. Our goal is to increase the adoption rate of 37M US adults with hearing loss, only 8M use hearing aids today. Founded by Auditory Neuroscientist & AI expert and a Hearing Aid hardware design expert.

GEn1E Lifesciences is a Clinical-stage, multi-target company with a unique AI platform. We develop novel, next-generation, immunomodulatory therapies for rare & inflammatory diseases with no effective treatments. Our team is supercharging the drug development cycle by applying AI to multiple-mechanism-of-action protein targets and their natural platform capabilities—creating novel therapeutics at an unprecedented pace. Our AI platform has enabled us to develop a purpose-built therapy for ARDS to reduce its $20 billion cost on society (just in the USA). GEn1E has built a rich pipeline of 21+ novel and selective immunomodulators and has plans to accelerate 2 additional devastating diseases (beyond their lead indication) to IND in the next 12 months. Our AI platform enables tremendous pace and capital efficiency as demonstrated by our progress in ~2 years with seed capital—a stark contrast to the typical spend of $100M+ and 7+ years exhibited in the pharmaceuticals / biotech industry. With ~90% of rare diseases having no therapeutic treatment at all, GEn1E is taking a giant swing that will hopefully bring life-saving therapies to the lives of patients in need. The team at GEn1E has decades of experience in drug development and machine learning. We graduated from YCombinator and Stanford-StartX in late 2019. We are based in Palo Alto, CA.

We are a service for people to learn about their personal environmental exposures. Our first product is a urine test for exposure to chemicals in everyday products.

Asher Bio is a biotechnology company developing precisely targeted immunotherapies for cancer and other diseases. Our cis-targeting platform aims to enable selective activation of specific immune cell types, addressing the inherent limitations of otherwise pleiotropic immunotherapies that act on multiple cell types. Our approach has the potential to precisely direct different immune mediators against a range of target immune cell-types and create best-in-class immunotherapies in cancer, autoimmune and infectious diseases. Asher Bio is backed by Third Rock Ventures and is located in South San Francisco.

Abalone Bio developed a technology to find antibody drugs that activate and modulate cell surface receptors, the “antennae” on cells that help convert chemical signals into cellular responses, like growth. Antibodies are a growing class of drugs that have tremendous safety and efficacy advantages over small molecules; 7 of the top 10 selling drugs are antibodies, earning an average of $7B in revenue. However, antibodies- especially ones that activate and modulate cell surface receptors- are hard to find. Abalone Bio expands the playing field for antibody therapeutics and enables us to previously access treatments for untreated diseases. We have already discovered a novel antibody that activates a non-opioid receptor that produces analgesia. We are developing this antibody into a treatment for neuropathic pain – a medical condition that currently is treated with drugs like addictive opiates. The same molecule is also a potential treatment for inflammatory and fibrotic diseases, all 1B+ markets.

We provide high quality data for AI radiology. We're building the biggest database of labeled medical data in the world, starting with radiology images. We sell to medical companies who are training and validating AI algorithms.

In 1935 the Social Security Act set the retirement age to 65. At the time, the average life expectancy of an American was 62. A lot has changed in the last 83 years. The average American now lives until 79. The people turning 65 today were 45 during the first dot-com boom. The fastest growing segment on Tik-Tok is seniors. It took 20 years, but the internet has finally arrived for seniors. But most of the products that seniors use are distinctly “pre-web” - they’re cumbersome and exploitative. When seniors buy healthcare, they have to talk to an insurance agent over the phone. These agents are exactly what you’d expect - they don’t know much about health insurance and they push Mom and Dad into the plan they get the highest commission on. When seniors look to for liquidity, reverse mortgage brokers take advantage of their financial illiteracy. When seniors look for companionship, they find themselves isolated in the suburbs they originally moved to to raise a family. We are acutely aware of these problems because we see our own parents experience them. Fair Square is fixing them. Fair Square’s goal is to be a company seniors trust. To advise them on health insurance and financial planning. To find them a book club or an Art History lecture at a local community college. To have the customer experience of a five-star hotel and the care and respect of a relative. We started by building a customer obsessed health insurance brokerage for seniors. We’ve worked with 10,000 people across the United States. Our NPS score is 98, compared to an industry average of 13. Join us and build the rest.

Altay develops small molecule drugs to treat chronic liver diseases like liver fibrosis and liver cancer. Our co-founder Dr. Osman Ozes, led the first drug development program for Esbriet (Pirfenidone), resulting in the first FDA approved therapy for lung fibrosis. Esbriet is now a $1 billion/year drug and has already made over $6 billion in revenue. With a team that has over 70+ years of small molecule drug development experience, we intend to do the same with chronic liver diseases, which affects over 20 million Americans and represents a market size of over $30 billion. We know we are well positioned for success because we have shown excellent pre-clinical mouse data in several liver fibrosis models using our novel small molecule. We demonstrate a reduction in fibrosis with our drug, but more significantly, we show a reversal in fibrotic tissue back to normal tissue. With our current developmental strategy, we hope to have a clinic-ready compound by the end of 2021 and be in phase I clinical trials by mid of 2022.

Fella Health is the telehealth clinic for men with obesity. With Fella, patients meet a board-certified obesity doctor to prescribe FDA-approved medications, while they undertake personalized health coaching through our app.

We are developing a drug to increase metabolism and burn calories without exercise. Obesity and type 2 diabetes have reached epidemic proportions. There are 2.2B overweight people and 500M people with type 2 diabetes worldwide, and these numbers increase drastically every year. Existing drugs are not effective enough to reverse the trend. Our drug can solve this problem, because it addresses the root cause of metabolic disorders – the imbalance between caloric intake and expenditure. Our drug will target mitochondria – the powerhouse of the cell – to generate heat. This approach has been proven to fully reverse obesity and type 2 diabetes in animals. However, therapeutic application for humans was impossible, because mitochondrial heat production could only be induced by highly artificial methods with side effects. This changed after our recent breakthrough discovery of the protein that mitochondria naturally use to generate heat. We have developed a unique high-throughput drug discovery platform to identify compounds that selectively activate this target protein, without side effects. For decades people have wanted a drug that burns calories like exercise does. We are realizing this dream at Equator Therapeutics.

Menten AI designs protein drugs and enzymes using quantum computing and machine learning. Their technology leapfrogs current computational methods making it possible to design previously intractable proteins. The team created the first protein design algorithm for current and near-term quantum computers and created the world’s first protein designed on a quantum computer. They are now working on 3 new proteins, including a peptide to prevent the spread of viruses like Covid-19. They have 2 paid pilot projects with multinational chemical companies and 4 LOI’s with pharma and biotech companies.

Ansa Biotechnologies is developing a new way to make DNA that will be faster, cleaner, and more accurate than existing methods. Currently, DNA is manufactured via a chemical method that has remained mostly unchanged for 35 years. Our enzyme-based approach promises to dramatically accelerate innovation in biological research and biotechnology, including therapeutics, diagnostics and biomanufacturing.

Osmind is the premier platform for clinicians and researchers advancing new life-saving mental health treatments. Today, mental health disorders are one of the leading causes of death worldwide, especially among young adults, and are tied to shortening lifespans. While there have been developments in new psychiatric medications since the first FDA approval in 1954, today there is a growing movement among clinicians, patients, and researchers who are recognizing the need to accelerate new science. The Osmind treatment platform is the first and only solution that solves specific challenges faced by neuropsychiatric clinics, spanning general psychiatry and interventional psychiatry (transcranial magnetic stimulation, ketamine, SPRAVATO®, psychedelic medicine, electroconvulsive therapy). The core electronic health record (EHR) technology is precisely developed for interventional treatment workflows and designed to support a strong therapeutic alliance, including journaling tools and assistance with health plan reimbursement, which is a significant access hurdle for millions of patients. Research from our platform is already helping to set new standards for mental health interventions. For example, in the largest published real-world analysis of ketamine infusion therapy for depression, we teamed up with Stanford University School of Medicine to share findings in the Journal of Affective Disorders (March 2022). We have multiple ongoing research studies leveraging our proprietary real-world data, including an even larger ketamine analysis leveraging machine learning to predict treatment outcomes. Osmind is a San Francisco–based public benefit corporation led by scientists, technologists, and psychiatrists. We are backed by top investors including DFJ Growth, General Catalyst, Future Ventures, Tiger Global, and Y Combinator.

Daybreak offers comprehensive and clinically-validated online mental health services designed for youth, like teletherapy, psychiatry and digital education. We partner with schools and pediatric groups to make access to services easy, and strive to deliver zero cost to the end consumer through insurance and government funding.

We help hospitals 🏥 hire nurses 🧑🏻‍⚕️ from all around the world 🌏 and with technology make the complexity of immigration and licensing simple.

We are making coffee for caffeine sensitive people. We do this by producing the world's first caffeine replacement, paraxanthine. It's better than caffeine at waking you up and causes fewer side effects, like anxiety and jitteriness.

Quadrant Eye is on a mission to improve eyecare access and fight preventable blindness. We're building the next generation eye exam... inside the average American home. Our team wants to enable patients' best and most visually rich lives. To this end, we're looking for curious and nimble minds to help us develop the world's first fully online eye exam and ultimately deliver high-quality eyecare at scale. Some QE highlights: 🐝 We're a team of surgeons, scientists, venture partners, and hackers who mean business. 💸 Our backers include Y Combinator, Khosla Ventures, and the creator of Google Image Search. 🍥 We're a mission-driven company tackling an eye health market worth $USD137B. 🌟 Our core focus is currently the development of patentable deep tech, and our overall vision is to change eyecare for good.

Nourish is solving America's healthcare crisis by helping people eat better. We connect chronic condition patients with a Registered Dietitian via telehealth and get it covered by their health insurance.

Leveraging AI to provide veterinarians with more accurate and affordable diagnostics.

Our mission is simple: challenge archaic rules and implied medical conventions in healthcare to better serve patients and physicians. Gradia is the backbone of the entire patient experience, helping patients get personalized, high-touch care while also making clinics more money. With our software patients can stay informed/educated about the status of their care, easily communicate with their providers, and get direct access to a specialized virtual care team. Our software is currently at several clinics across the Southeastern US and helping thousands of patients get the care they deserve.