Health Tech Startups funded by Y Combinator (YC) in the San Francisco Bay Area 2026

Our Why At Clipboard, our mission is to uplift as many communities as possible. We do this by connecting professionals with the workplaces that need amazing workers, helping people achieve financial stability for themselves and their families all across the U.S. Our How Clipboard is an app-based marketplace where workplaces post calls for help and workers answer. Every year, we help hundreds of thousands of workers fill millions of shifts across the U.S. We’re the leader in Long-Term Care staffing and are rapidly expanding into Home Health, Hospitals, and more. Our Team Founded in 2016, we are a remote-first team of over 1,000 people working to uplift communities across the country.

Your skin is yours, but understanding it has never felt that way. Getting answers has meant an appointment, a price, and a long trial-and-error process. We're changing that. Lumeria puts your skin in your own hands: the power to see it, know it, and own its story yourself, at home and on your terms.

RonanRX helps you personalize GLP-1s like Ozempic, peptides, and other treatments using your labs, wearables, medical history, treatment response, and the latest medical research. Instead of treating the average patient, we continuously personalize your treatment as your body changes. We've built the complete feedback loop for personalized medicine: your health data automatically syncs into one place, AI helps personalize treatment, licensed doctors make prescribing decisions, medications are delivered to your door, and every outcome continuously improves your protocol. Connect your health data once. RonanRX automatically syncs your labs, wearables, and medical records into a single AI-powered health profile that helps personalize GLP-1s like Ozempic, peptides, supplements, and other treatments around your biology. If prescribed, your medication is delivered to your door. Our founders have built and exited multiple companies, raised over $100M, and previously built a $50M U.S. medical manufacturing business. Start with a text at RonanRX.com and become the maximum version of yourself,

Illume is a 24/7 AI personal health & longevity companion that connects your wearables, blood panels, and genomic data to text you personalized and actionable insights. We pull in your health data and fuse it into one secure model. You get daily text updates on what changed, what it means, and what to do next; conversational health Q&A like "What should I do to improve my bloodwork?"; cross-data trend detection that catches patterns individual platforms miss; and a full platform to dig deeper, explore your health data, and text your Illume agent anytime. We're 3 MIT grads & friends, with experience at Windsurf, MIT CSAIL, Eli Lilly, & the Broad Institute.

Insurf is the AI-native data and decision layer for health insurance. Our first product, Inveto, automatically turns denied healthcare claims into source-cited, physician-attested appeals, recovering revenue practices lose today. Every claim it resolves builds the coverage-decision graph, the proprietary dataset of real payer behavior that powers our next product, Surely, which prices the true cost of a health plan for employers and brokers.

Kaigo Health provides an AI-powered outpatient care management platform that automates and scales remote care management for Medicare patients including post-discharge followups, ongoing check-ins, and monitoring. Using phone calls as an age-friendly interface, we aggregate patient responses, voice biomarkers, and remote patient monitoring data for powerful preventative and proactive healthcare.

LunaBill is building AI Voice callers for healthcare billing teams. Insurance claim follow-up calls account for the 80% of the daily workload of a healthcare billing team, with each call averaging 30 minutes. Since our launch in July we are now at $764K in contracted ARR, of which $428K is live revenue and the rest will go live by January 2026. Our customers see a 10x increase in claims followed up per biller in the first week and we have converted 100% of pilots to paying customers. We have automated 50,000+ calls and signed partnerships with top healthcare leaders like UC health systems, Mayo, Experian Health and more. The founders have known each other for over a year. Suhail is a 2x founder, with 3+ years of experience building in healthcare including operating a medical billing company with 200+ healthcare clients. David founded Skiesoft, Taiwan’s biggest healthcare AI scribe company, used by thousands of healthcare professionals. He also worked as a data scientist at UCSF, building models to audit medical-coding accuracy. Yash was a researcher at various hospital systems including Mayo Clinic.

Our mission is to quantify and improve how people look and feel using data from blood panels, DEXA scans, skin analysis, hair analysis, and many other tests. We evaluate a baseline, give clear steps on how to improve, and measure progress over time.

Clicks Health builds AI agents that automate back-office operations for RCM companies and healthcare providers. Our agents work across EHRs, payer portals, desktop applications, and legacy systems, following existing processes, handling exceptions, and escalating when human judgment is needed. Backed by Y Combinator, Clicks helps teams improve accuracy, shorten turnaround times, and reduce operating costs, with SOC 2 Type II and HIPAA compliance built in.

Adentris is an AI compliance copilot for hospitals and clinics. We are like Grammarly for doctors, finding and fixing mistakes that lead to denied insurance claims or patient lawsuits. The industry today spends $40B doing this manually.

Your wearable tells you what happened. Amby texts you what to do next, checks in, and adjusts when life gets in the way.

Mecha Health builds foundation models to automate x-ray analysis for radiologists. We take medical images and process them using proprietary models to produce accurate draft medical reports. Our first model was built in less than two months, and beat Microsoft, Google, and OpenAI on clinical accuracy metrics. On top of that, it’s two orders of magnitude smaller and trained with a quarter of the data. We are partnering with the largest privately owned radiology practice in the US and a multinational tele-radiology company to provide them with their own foundation model, enabling their radiologists to go from reading 1 scan per hour to 1 scan every 5 minutes. By charging on a per scan basis, x-ray report generation represents a 40B+ market opportunity.

We’re Toothy.ai. We’re building AI agents for dental practices that handle everything related to patient insurance. The average dental clinic spends over 160 hours a month on insurance tasks like verifying patient policies, billing, and claims processing. Our AI agents automate this entire workflow—including making insurance calls with voice AI—saving clinics time, reducing costs, and ensuring faster reimbursements.

Asteroid is the AI-powered integration layer for healthcare. One connector for EHRs, payer portals, and legacy desktop systems, with 100+ pre-built integrations that go live in days, not months. Built for developers and operations teams, with integrations that maintain themselves.

HealthSpark empowers physical therapists (PTs) to start, run, and grow their own independent practices. Our AI-native “business-in-a-box” takes care of the administrative work—credentialing, insurance billing, patient onboarding, documentation, and scheduling—so PTs can focus on patient care, not paperwork.

Careforce builds AI Workers for healthcare orgs to take on coordination burden from staff and reduce time of care by autonomously identifying and outreaching patients (through phone, text, email, & mail) to schedule visits, book screenings, complete pre-post, and onboard. These agents require no integration, can navigate all tools, speak 29 languages, come with 50+ outreach scripts and have a remarkable 80% conversation-to-booking closing rate.

Planbase has everything health clinics need to manage their team in one place: capacity planning, employee scheduling, credentialing and payroll.

Dodo turns client communication into booked appointments, completed workflows, and predictive analytics, powering millions of client interactions annually for hundreds of clinics. Our multi-agent system autonomously runs scheduling, refills, intake, and follow-ups across calls and texts — integrating directly with clinic systems to cut communication overhead ~70% and act like a trained CSR 24/7.

At Brighterway, we use AI to speed up the medical record review process in the Workers' Compensation Industry. Physicians and claims handlers spend hours reviewing thousands of pages of medical documents– our technology highlights the information that is most relevant to a doctor's specialty or a given injury, streamlining their review process and saving them time. Brighterway structures and deduplicates disorganized medical records (PDFs) and extracts the content that is medically relevant and related to a given claim, so they can focus on what matters most.

Burdensome documentation is the #2 reason causing burnout for physical therapists. More than half of all physical therapists have to write documentation in their free time without pay. up to 2 hours a day. Our AI Scribe listens, generate first draft of clinical documentation in minutes, and sync reviewed documentation to EMR in 2 seconds. With us, clinicians can finish documentation 70% faster and become happier.

All-in-one RTM platform designed for physical therapy and powered by AI

At Arini, we’re building the operating system for dental groups. Phones are the backbone of dental operations — 80% of appointments are still booked over the phone — yet practices miss 20–30% of inbound calls. That’s millions in lost revenue every month. Patient engagement is the biggest bottleneck to growth in dentistry, and we’ve built the most comprehensive AI-powered patient engagement suite in the industry. Arini manages calls, texts, and bookings. We’re going after a $220B, overlooked industry that still runs on legacy systems and outdated workflows. Arini is bringing AI to every part of the dental stack.

Scritch is building the leading AI systems for veterinary medicine, starting with voice agents that automate front-desk operations in veterinary practices.

Andy is AI software that completes documentation for nurses doing home visits. Our software saves $8B a year; Tiantian was previously a PM at Google’s healthcare business and Max was a staff engineer on the health team at Apple. Andy benefits nurses and the agencies that employ them. Agencies that use Andy see up to 45% more detailed charts, 2x greater nurse productivity, and timely submission (no more billing delays!) With Andy, clinicians get their evenings back. Home health is the fastest growing segment of healthcare, doubling to $251B by 2031. Combined with recent nursing shortages and burnout, we’re seeing not just urgency, but excitement and joy, around adopting AI for home health.

Shasta Health builds AI agents to handle patient calls, verify insurance and automate admin tasks for healthcare clinics

Cair Health empowers billing companies, care management platforms, EHRs, offshore BPOs, provider groups, and specialty pharmacies with AI-driven RCM solutions. Our suite of AI Agents helps RCM teams streamline operations, reduce manual costs, and improve consistency—while maintaining full control over core workflows. Cair is trusted by 100+ practices across the country — including iconic VC-backed digital health startups, leading specialty EHRs, and some of the largest billing companies and BPOs Backed by Y Combinator, Foundation Capital, Soma Capital, Translink Capital & many others..

Auricle is a medical device company building a breakthrough neurostimulation implant to restore hearing in millions of patients who no longer benefit from hearing aids, get less than 60% on a word recognition test, but aren't prepared to make the jump to a cochlear implant. Our approach preserves remaining natural hearing through a reversible and less invasive surgery, addressing the key concerns that hold most patients back from getting a cochlear implant (currently the only treatment option for these patients). The company spun out of Stanford Biodesign having completed two acute human clinical studies demonstrating the approach will work. The team is now focused on developing their full implant system for their first clinical trial. Auricle addresses a currently unserved profile of hearing loss that affects a growing population of 3.5 million patients in the US and represents an immediately accessible $1.2B market opportunity with existing reimbursement.

There are billions of dollars of hospital waste caused by inefficient, disconnected supply chains and finance data. Today, clinics are facing unprecedented backorders, recalls, and purchase verticals (medical devices, SaaS, security, commodities). We are building a single product to 10x a fragmented industry with each tool built almost 20 years ago.

At InVision, we use AI to help streamline the interpretation of ultrasounds and identify diseases that may have been missed by human readers. Our models have been tightly integrated into the clinical workflow to allow easy usage by clinicians. Our work has previously been peer-reviewed and published in several top medical venues, including Nature (2020), Nature Medicine (2021), Lancet Digital Health (2021), JAMA Cardiology (2022). Results from our blinded and randomized clinical trial on evaluating cardiac function have also been recently presented as a Late Breaking Clinical Trial at the European Society of Cardiology.

Entvin is building AI agents specifically designed to support regulatory teams in the life sciences industry. Our platform leverages AI to streamline workflows, automate complex tasks, and enhance efficiency throughout the regulatory process. By focusing on the unique needs of regulatory teams, we help companies navigate compliance, accelerate approvals, and reduce operational bottlenecks, all while ensuring data security and confidentiality.

We’re on a mission to leverage AI and voice technology to solve inefficiencies and revenue leakage in our healthcare system. With the rise of EHRs, the manual documentation burden on doctors has never been higher, leading to burnout and fatigue and high attrition rates. Assigning the correct diagnosis and billing codes is crucial for proper reimbursement and patient care, but medical coding is becoming more and more complex each year with growing numbers of codes (over 145,000 now), and doctors are unsupported by current technology to keep up with its ever increasing requirements. $125 billion is left on the table each year by healthcare organizations due to improper documentation and coding. Knowtex creates visit notes with up-to-date and accurate reimbursement codes from doctor-patient conversations, allowing the doctor to focus on patient care and preventing revenue leakage for hospital systems through standardized, transparent, and accurate documentation.

Malama offers doula-led holistic support during and after pregnancy at no cost to patients. Malama is in-network with Aetna, UnitedHealthcare, Anthem, Kaiser, and several Medicaid Managed Care Plans. Malama is backed by the Stanford d.school, Y Combinator (S22), Alpine Investors and more.

Delfino AI helps automate the repetitive phone calls that providers' offices make to payors

We deal with drugs that cost on average $70,000/patient per year. These patients need their medications within days but currently it takes weeks because of complex, manual workflows that were built around poor data standards. At Lamar Health, our mission is to get patients on therapy fast. Our customers are specialty pharmacies, infusion clinics and hospitals that are moving quickly to use AI to offset operational risks and gain competitive advantage.

RTHM is the self-learning digital clinic for medicine's new normal: complex patients with lots of data and/or multiple chronic conditions. We are focused on infection-associated chronic conditions and autoimmune conditions impacting 70M individuals in the US.

Digital health holds a lot of potential but is ignoring a growing problem: diagnostic testing. Without this data, providers and organizations will be limited in the services they can provide patients at home. Scout has developed a platform - Hub, test kits, and app - that delivers health testing at home with 10x lower development cost and 3x lower per-test price. Our patented tech also meets performance requirements for medical diagnoses and integrates with the current healthcare tech stack. Scout’s technology is poised to disrupt the outdated $33Bn diagnostic market by democratizing testing while dramatically improving the patient experience. Scout has received $16M in non-dilutive funding from the NIH and other organizations to fully de-risk our platform, and our pipeline includes a diverse test menu for primary care (e.g. respiratory and sexual health), wellness (e.g. gut health), and chronic conditions (e.g. certain cancers). We have already received FDA authorization for our platform in clinical settings and are planning to launch our flagship Scout Hub in 2024.

US hospitals and clinics are losing $125B every year due to delayed and inaccurate medical coding. Arintra is solving this problem by automating medical coding using clinical AI. Arintra converts a patient chart instantly into insurance claims with 96% accurate medical codes and zero human intervention. Arintra has partnered with several provider clients that includes health systems and large physician groups with 100% success. Through automation of these charts, Arintra has reduced undercoding by 11% and coding-related claim denials by 43%. Arintra is headquartered in Austin, Texas. Arintra is bi-directionally integrated with leading EHRs including Epic, Athena, Cerner, etc. to process patient charts directly from the EHR to create a direct-to-billing claim. This direct-to-billing claim includes precise E/M levels, CPT, ICD-10, HCC, HCPCS codes with appropriate modifiers and units. Both founders have PhDs in AI, significant ML and NLP experience, 60+ patents and publications, and a combined 20+ years of experience working at B2B companies and startups in Silicon Valley.

Building a standard-of-care medical device to freeze abnormal cells before they become cervical cancer, in any clinic, anywhere in the world, at 1/10 the cost. -- Ananya Health is building a portable cryoablation unit designed for every primary care clinic in the world. Our beachhead application is cervical cancer prevention -- even though cervical cancer is easy to screen for, 80% of clinics worldwide lack the infrastructure and specialized staff to treat at the earliest stages. Our platform technology allows nurses and lower level health workers to treat at the point of care for 1/10 the cost of traditional ablation, and is the only cryo device that will help us achieve the WHO target to eliminate cervical cancer in our lifetime.

Sully.ai is printing labor for health systems by building a team of autonomous AI agents to run the entire hospital operations. The autonomous agents run like ClawdBot in the background (Receptionists, Medical Consultant, Triage Nurse, Scribes, Coders) collaborate to execute entire workflows. Replacing the $800B labor doing all the manual work at hospitals.

Osmind is the premier platform for clinicians and researchers advancing new life-saving mental health treatments. Today, mental health disorders are one of the leading causes of death worldwide, especially among young adults, and are tied to shortening lifespans. While there have been developments in new psychiatric medications since the first FDA approval in 1954, today there is a growing movement among clinicians, patients, and researchers who are recognizing the need to accelerate new science. The Osmind treatment platform is the first and only solution that solves specific challenges faced by neuropsychiatric clinics, spanning general psychiatry and interventional psychiatry (transcranial magnetic stimulation, ketamine, SPRAVATO®, psychedelic medicine, electroconvulsive therapy). The core electronic health record (EHR) technology is precisely developed for interventional treatment workflows and designed to support a strong therapeutic alliance, including journaling tools and assistance with health plan reimbursement, which is a significant access hurdle for millions of patients. Research from our platform is already helping to set new standards for mental health interventions. For example, in the largest published real-world analysis of ketamine infusion therapy for depression, we teamed up with Stanford University School of Medicine to share findings in the Journal of Affective Disorders (March 2022). We have multiple ongoing research studies leveraging our proprietary real-world data, including an even larger ketamine analysis leveraging machine learning to predict treatment outcomes. Osmind is a San Francisco–based public benefit corporation led by scientists, technologists, and psychiatrists. We are backed by top investors including DFJ Growth, General Catalyst, Future Ventures, Tiger Global, and Y Combinator.

Bunkerhill is the agentic AI platform for health systems. Turn your ideas into reality. Backed by Sequoia and Khosla.

NoDraw by Tambua Health is the world’s first bloodless, blood diagnostic app, turning any smartphone into a full blood panel diagnostic tool

Segmed provides at-scale access to novel clinical data globally, offering millions of diagnostic-grade medical images to accelerate innovation and mature the evidence needs of life sciences and technology industry. ‍ Our solutions allow you to access a Real World Data (RWD) network to facilitate rapid discovery and investigational capability of imaging data, development of early disease detection & prediction models, improved patient recruitment and reduced operating burden to access therapeutic data ecosystem.

Our overarching mission is to build the AI operating system for consumer healthcare - delivering end-to-end care with near-zero marginal human time. We believe the future of healthcare is automated, intelligent, radically lower cost, and built around the consumer. We believe biology is entering a golden age. We believe profitable, focused companies beat bloated ones. We're determined to get the humans out of healthcare - replacing slow, expensive, legacy workflows with software-driven care delivered at scale. We’ve started by building this infrastructure to power our own brands - including Bolt Pharmacy and Fella Health, among others. Today, that infrastructure is helping patients access life-changing treatment for excess bodyweight. Over time, we’ll extend it across many of the categories that will define the next era of healthcare. Our infrastructure will have served 100 million patients worldwide by 2035. We’ll then use that infrastructure to deliver next-generation healthcare products at massive scale. In doing so, we aim to build the world’s first trillion-dollar healthcare company.

Pair Team is building a new kind of healthcare system across Medicaid, Medicare, and public assistance programs: one that recognizes that access to housing, nutritious food, and reliable transportation are just as critical to health as having the right medications or seeing a doctor. We run one of the largest medical groups for complex, low income patients and our next chapter is building a vertically integrated AI care manager to support any clinical, behavioral, or social need for everyone.

We help healthcare companies run their practices. Eligibility, BI, claims, patient payments? Shoot us an email at founders@aperohealth.com Apero is a Y-Combinator-backed startup based in San Francisco bringing transparency and ease to medical billing. As one of the top startups from the Summer 2019 Y Combinator batch, we have raised from well-known investors including the creator of Gmail Paul Buchheit and the founders of Doctor on Demand, Gusto and Reddit, and serve startups that have raised over $1B in Venture Capital. The founding team are Stanford CS and Berkeley grads and include the CTO of Doctor on Demand having helped raised $240m and process millions of video calls. We are also hiring for engineers and product-minded operations people interested in giving price transparency to patients and providers. We serve practices nationwide, and integrate with leading EHRs as well.

YourChoice Therapeutics is revolutionizing the global contraceptive market. Our vision is to develop non-hormonal contraceptives to provide both women and men with birth control options that lack the associated risks of hormone-based options but are equally effective. Traditionally, it has been the women’s financial and health burden to have a contraceptive in place. Our first goal is therefore to bring a novel non-hormonal, on-demand and low cost female contraceptive to the market that will substantially improve their quality of life and well-being. Our second goal is to develop the first ever non-surgical and highly effective non-hormonal contraceptive for men. Currently, male contraception is limited to two main options – vasectomy or condoms. Having such options available to both women and men will globally allow for much better family planning, reduce the number of unwanted pregnancies including abortions and therefore reduce costs and ensure contraceptive health and well-being.

Probably Genetic is changing the lives of patients living with severe, complex diseases. Our data platform is used by drug developers and patient advocacy groups to develop and launch treatments for these patients. Our technology discovers undiagnosed patients online, analyzes their disease state using machine learning and at-home testing, and enables compliant communication with patients. In doing so, we help patients access diagnoses, clinical trials, and treatments as early as possible.

BrainKey is an AI-driven digital healthcare company with a mission to create a world free from dementia.

LemonBox is an AI-driven personalized nutrition company. Using generative AI nutrition（AI 生成式定制营养）, LemonBox analyzes each user's dietary habits, health goals, and biometric data to generate a custom daily supplement formula — then produces and delivers it as a personalized day pack via monthly subscription. Founded in Silicon Valley in 2016 and backed by Y Combinator, Bessemer Venture Partners, and Partech Ventures, LemonBox has served over 10 million users globally.